Drug Information

  



   








 




Pharmacokinetics

Ergotamine is erratically absorbed from the GIT.Oral
absorption is incomplete.It undergoes extensive first pass metabolism.

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Indication & Dosage

Sublingual

MIGRAINE, CLUSTER HEADACHE: Ergotamine tartrate 1-mg,
Caffeine-100mg. Early treatment is important. 2 tabs sublingually
repeated if necessary at 30 minutes intervals. Maximum 6 tablets/day.
Children 3-9 yrs-quarter adult dose. 10-14 yrs-half adult dose.

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Action

Ergotamine causes
constriction of peripheral and cranial blood vessels. the amplitude of
pulsations in the cranial arteries is reduced as is also extra cranial
blood flow. ergotamine also reduces hyperperfusion in the basilar artery
territory. Caffeine potentiates the action of ergotamine.

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Interactions

When it is used along with Cocaine or parenteral Epinephrine adverse
effects caused by ergotamine may be increased.

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Adverse Effect
& Precautions




Epigastric distress, nausea,
vomiting, cold extremities & tingling of extremities.

The chance of adverse effects may be increased in patients with
Hypertension, pruritis, renal disease, hepatic disease, Mental
depression, hyperthyroidism, intestinal obstruction and Urinary tract
obstruction.

Pregnancy: Contraindicated.

Breast Feeding: Use with caution.

Man: May be given in reduced dose.

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Brands available in market











MIGRANIL Inga
(Ergotamine
tartrate 1mg, caffeine 100mg, belladonna dry extract 10mg paracetamol
250mg; tabs Migraine & cluste headache; 10
14.95
MIGRIL

Burroughs
Wellcome
(Ergotamine
tartrate 2mg, cyclizine hcl 50mg, caffeine 100mg; tabs for relief of
acute migraine attack. Cluster headache. 10
13.80
VASOGRAIN

Cadila
Pharma
(Ergotamine
tartrate 1mg, caffeine 100mg, Paracetamol 250mg, Prochlorperazine
maleate 2.5mg; tabs Migraine. Vascular headache & Cluster headache.
10
8.10



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Drug Information
  

   

 

Pharmacokinetics

Ergotamine is erratically absorbed from the GIT.Oral absorption is incomplete.It undergoes extensive first pass metabolism.

Top
    

Indication & Dosage

Sublingual
MIGRAINE, CLUSTER HEADACHE: Ergotamine tartrate 1-mg, Caffeine-100mg. Early treatment is important. 2 tabs sublingually repeated if necessary at 30 minutes intervals. Maximum 6 tablets/day. Children 3-9 yrs-quarter adult dose. 10-14 yrs-half adult dose.

Top
    

Action

Ergotamine causes constriction of peripheral and cranial blood vessels. the amplitude of pulsations in the cranial arteries is reduced as is also extra cranial blood flow. ergotamine also reduces hyperperfusion in the basilar artery territory. Caffeine potentiates the action of ergotamine.

Top
    

Interactions

When it is used along with Cocaine or parenteral Epinephrine adverse effects caused by ergotamine may be increased.

Top
  

Adverse Effect & Precautions

Epigastric distress, nausea, vomiting, cold extremities & tingling of extremities.

The chance of adverse effects may be increased in patients with Hypertension, pruritis, renal disease, hepatic disease, Mental depression, hyperthyroidism, intestinal obstruction and Urinary tract obstruction.
Pregnancy: Contraindicated.
Breast Feeding: Use with caution.
Man: May be given in reduced dose.

Top
  

MIGRANIL

Inga

(Ergotamine tartrate 1mg, caffeine 100mg, belladonna dry extract 10mg paracetamol 250mg; tabs Migraine & cluste headache; 10

14.95

MIGRIL

Burroughs Wellcome

(Ergotamine tartrate 2mg, cyclizine hcl 50mg, caffeine 100mg; tabs for relief of acute migraine attack. Cluster headache. 10

13.80

VASOGRAIN

Cadila Pharma

(Ergotamine tartrate 1mg, caffeine 100mg, Paracetamol 250mg, Prochlorperazine maleate 2.5mg; tabs Migraine. Vascular headache & Cluster headache. 10

8.10

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By |2022-07-20T16:44:55+00:00July 20, 2022|Uncategorized|Comments Off on Ergotamine

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