Drug Information

  


      






 

Pharmacokinetics

Erythromycin is absorbed from the small intestine, the
drug gets partially destroyed by the gastric juice so it must be
administered in enteric coated form. It is mainly concentrated in the
bile.

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Indications & Dosage

Oral

ACUTE BACTERIAL PHARYNIGITIS TONSILLITIS, SINUSITIS, OTITIS,
MASTOIDITIS, EPIGLOTTITIS, BRONCHITIS, PNEUMONIA ERYSIPELAS, WHOOPING
COUGH, CELLULITIS, CARBUNCLE, PYODERMA, DIPHTHERIA, LEGIONNAIRE’S
DISEASE CHACROID, UROGENITAL INFECTIONS:
Usual dose 1g daily b.i.d/q.i.d
Upto 4g/day can be given in severe infections. Legionnaire’s disease:
500mg-1g 6 hrly. Streptococcal prophylaxis: 250mg 12 hrly. Children
30-50mg/kg/day in 3-4 divided doses. May be doubled in severe
infections. Elderly: Maximum daily dose 1.5g.

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Action

Primarily bacteriostatic against a wide range of
organisms. Erythromycin is used as an alternative to tetracyclines in
chlamydial infections. It is also used in diphtheria, pertussis,
legionnaire’s disease and other respiratory tract infections. Also used
topically in acne vulgaris.

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Interactions

With Acetaminophen, Amiodarone or Anabolic steroids, Androgens,
antithyroid agents, Carmustine, Chloroquine, Dantrolene, Daunorubicin,
Disulfiram, Divalproex, Estrogens, Gold salts, Hydroxychloroquine,
Mercaptopurine, Methotrexate, Methyldopa, Naltrexone: Use of these drugs
with erythromycins, especially erythromycin estolate, may increase the
incidence of hepatic disorders.

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Adverse
Effect & Precaution




Local irritation, redness, pruritis.

In cardiac disease:
High doses of erythromycin may increase the chance of adverse effects in
patients with a history of an arrhythmias. Hepatic disease
:Erythromycins, especially erythromycin estolate, may increase the
chance of adverse effects involving the liver. Loss of hearing : High
doses of erythromycins may, on rare occasion, cause hearing loss and
ototoxicity, especially in renal or hepatic disease.

Pregnancy: Use with caution.

Breast Feeding: Use with caution.

Man: May be used.

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ALTHROCIN

Alembic
TAB 250mg 10 42.12
TAB

500mg


10


83.40
DIS-TAB 250mg 10 42.01
CHEW-TAB 100mg 10 18.93
DROPS 100mg/ml 10ml 21.84
KID-TAB

125mg
10 21.57
LIQUID 125mg/5ml 60ml 32.32
CITAMYCIN

Citadel
TAB 250mg 10 35.64
P-TAB 125mg 10 17.72
E-MYCIN

Themis Pharma
TAB 250mg 10 36.01
E.E.S.400

Abbott
TAB 400mg 10 69.50
ELTOCIN

IPCA
LIQUID 100mg/5ml 60ml 26.97
TAB 250mg

10
35.56
TAB 500mg 10 68.70
ELUCIN

Ind-Swift
TAB 333mg 10×10 645.00
SUSP 125mg/5ml 60ml 39.95
EROATE

Lupin(Div II)
TAB

250mg
10 35.64
TAB 500mg 10 67.49
SYRUP 125mg/ml 60ml 27.03
EROMED SUS

Comed
SUSP 125mg/5ml 60ml 29.14
EROMED -333

Comed
TAB 333mg 10×10 577.50
EROTECH 250

Yash
TAB 250mg 10×10 425.40
EROTECH 500

Yash
TAB 500mg 6×10 505.62
ERYBEST

Blue Cross
TAB 250mg 10 35.64
DIS-TAB 125mg 10 17.12
ERYC-S

BDH
(Erythromycin as stearate)


TAB 250mg 10 37.22
(Erythromycin as estolate)


TAB 250mg 10 41.97
DRYSYRUP 125mg/5ml 60ml 32.28
(Erythromycin as stearate)


KID-TAB 125mg 10 21.14
ERYMER

Mercury
TAB 250mg 10 32.50
SYRUP 125mg/5ml 45ml 19.80
ERYNATE

Hindustan Antibiotic
SUSP 100mg/5ml 45ml 12.95
ERYSPANS

American Remedies
CAPS 250mg 10 42.00
ERYSTER

Hindustan Antibiotics
TAB 250mg 10 33.42
ERYTHROCIN

Abbott
DROPS 100mg/ml 10ml 24.22
SYRUP 125mg/5ml 60ml 21.24
GRAN 400mg 6 41.75
SUSP 100mg/5ml 30ml 14.85
SUSP 100mg/5ml 60ml 24.11
ERYTHROCIN-FT

Abbott
TAB 100mg 10 13.96
TAB 250mg 10 33.10
TAB 500mg 6 38.57
ETOMIN

Sun Pharma
TAB 125mg 10×10 214.50
TAB 250mg 2x5x10 417.80
TAB 500mg 10×10 827.10
SUSP 125mg/5ml 60ml 32.14
INDERYTH

Indoco
TAB 250mg 10 42.01
SUSP 125mg/5ml 60ml 32.32
REXCIN

Rekvina Labs
KID-TAB 125mg 10 21.50
TAB 250mg 10 41.20
TAB 333mg 10 54.00
RESTOMYCIN

Astra-IDL
FC TABS 250mg 10 29.85
THROMYCIN

IDPL
TAB 250mg 10 34.66
SYSRUP 100mg/5ml 45ml 21.44
ACNEDERM

Abbott
LOTION 2% 20ml 27.00
ONIT 2% 10gm 16.00
ACNESOL

Systopic
GEL 4% 20gm 41.00
SOLN 2% 30ml 44.44
EROMED LOTION

Comed
LOTION 2% 30ml 36.75
ERYACNE

Galderma
GEL 4% w/w 20g 37.50
ERYTOP

USV
CREAM 3% w/w 20g 26.85
LOTION 3% w/v 25ml 30.98
GERY OINT

Geno
OINT 3% w/w 15g 26.68
REKCIN SOLUTION

Rekvina Pharma
SOL 2% w/w 30ml 37.50



Top


   






 

   

  
Drug Information
  

      

 
Pharmacokinetics

Erythromycin is absorbed from the small intestine, the drug gets partially destroyed by the gastric juice so it must be administered in enteric coated form. It is mainly concentrated in the bile.

Top
    

Indications & Dosage

Oral
ACUTE BACTERIAL PHARYNIGITIS TONSILLITIS, SINUSITIS, OTITIS, MASTOIDITIS, EPIGLOTTITIS, BRONCHITIS, PNEUMONIA ERYSIPELAS, WHOOPING COUGH, CELLULITIS, CARBUNCLE, PYODERMA, DIPHTHERIA, LEGIONNAIRE’S DISEASE CHACROID, UROGENITAL INFECTIONS:
Usual dose 1g daily b.i.d/q.i.d Upto 4g/day can be given in severe infections. Legionnaire’s disease: 500mg-1g 6 hrly. Streptococcal prophylaxis: 250mg 12 hrly. Children 30-50mg/kg/day in 3-4 divided doses. May be doubled in severe infections. Elderly: Maximum daily dose 1.5g.

Top
    

Action

Primarily bacteriostatic against a wide range of organisms. Erythromycin is used as an alternative to tetracyclines in chlamydial infections. It is also used in diphtheria, pertussis, legionnaire’s disease and other respiratory tract infections. Also used topically in acne vulgaris.

Top
    

Interactions

With Acetaminophen, Amiodarone or Anabolic steroids, Androgens, antithyroid agents, Carmustine, Chloroquine, Dantrolene, Daunorubicin, Disulfiram, Divalproex, Estrogens, Gold salts, Hydroxychloroquine, Mercaptopurine, Methotrexate, Methyldopa, Naltrexone: Use of these drugs with erythromycins, especially erythromycin estolate, may increase the incidence of hepatic disorders.

Top
    

Adverse Effect & Precaution

Local irritation, redness, pruritis.

In cardiac disease: High doses of erythromycin may increase the chance of adverse effects in patients with a history of an arrhythmias. Hepatic disease :Erythromycins, especially erythromycin estolate, may increase the chance of adverse effects involving the liver. Loss of hearing : High doses of erythromycins may, on rare occasion, cause hearing loss and ototoxicity, especially in renal or hepatic disease.
Pregnancy: Use with caution.
Breast Feeding: Use with caution.
Man: May be used.

Top
    

ALTHROCIN

Alembic

TAB

250mg

10

42.12

TAB

500mg

10

83.40

DIS-TAB

250mg

10

42.01

CHEW-TAB

100mg

10

18.93

DROPS

100mg/ml

10ml

21.84

KID-TAB

125mg

10

21.57

LIQUID

125mg/5ml

60ml

32.32

CITAMYCIN

Citadel

TAB

250mg

10

35.64

P-TAB

125mg

10

17.72

E-MYCIN

Themis Pharma

TAB

250mg

10

36.01

E.E.S.400

Abbott

TAB

400mg

10

69.50

ELTOCIN

IPCA

LIQUID

100mg/5ml

60ml

26.97

TAB

250mg

10

35.56

TAB

500mg

10

68.70

ELUCIN

Ind-Swift

TAB

333mg

10×10

645.00

SUSP

125mg/5ml

60ml

39.95

EROATE

Lupin(Div II)

TAB

250mg

10

35.64

TAB

500mg

10

67.49

SYRUP

125mg/ml

60ml

27.03

EROMED SUS

Comed

SUSP

125mg/5ml

60ml

29.14

EROMED -333

Comed

TAB

333mg

10×10

577.50

EROTECH 250

Yash

TAB

250mg

10×10

425.40

EROTECH 500

Yash

TAB

500mg

6×10

505.62

ERYBEST

Blue Cross

TAB

250mg

10

35.64

DIS-TAB

125mg

10

17.12

ERYC-S

BDH

(Erythromycin as stearate)

TAB

250mg

10

37.22

(Erythromycin as estolate)

TAB

250mg

10

41.97

DRYSYRUP

125mg/5ml

60ml

32.28

(Erythromycin as stearate)

KID-TAB

125mg

10

21.14

ERYMER

Mercury

TAB

250mg

10

32.50

SYRUP

125mg/5ml

45ml

19.80

ERYNATE

Hindustan Antibiotic

SUSP

100mg/5ml

45ml

12.95

ERYSPANS

American Remedies

CAPS

250mg

10

42.00

ERYSTER

Hindustan Antibiotics

TAB

250mg

10

33.42

ERYTHROCIN

Abbott

DROPS

100mg/ml

10ml

24.22

SYRUP

125mg/5ml

60ml

21.24

GRAN

400mg

6

41.75

SUSP

100mg/5ml

30ml

14.85

SUSP

100mg/5ml

60ml

24.11

ERYTHROCIN-FT

Abbott

TAB

100mg

10

13.96

TAB

250mg

10

33.10

TAB

500mg

6

38.57

ETOMIN

Sun Pharma

TAB

125mg

10×10

214.50

TAB

250mg

2x5x10

417.80

TAB

500mg

10×10

827.10

SUSP

125mg/5ml

60ml

32.14

INDERYTH

Indoco

TAB

250mg

10

42.01

SUSP

125mg/5ml

60ml

32.32

REXCIN

Rekvina Labs

KID-TAB

125mg

10

21.50

TAB

250mg

10

41.20

TAB

333mg

10

54.00

RESTOMYCIN

Astra-IDL

FC TABS

250mg

10

29.85

THROMYCIN

IDPL

TAB

250mg

10

34.66

SYSRUP

100mg/5ml

45ml

21.44

ACNEDERM

Abbott

LOTION

2%

20ml

27.00

ONIT

2%

10gm

16.00

ACNESOL

Systopic

GEL

4%

20gm

41.00

SOLN

2%

30ml

44.44

EROMED LOTION

Comed

LOTION

2%

30ml

36.75

ERYACNE

Galderma

GEL

4% w/w

20g

37.50

ERYTOP

USV

CREAM

3% w/w

20g

26.85

LOTION

3% w/v

25ml

30.98

GERY OINT

Geno

OINT

3% w/w

15g

26.68

REKCIN SOLUTION

Rekvina Pharma

SOL

2% w/w

30ml

37.50

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By |2022-07-20T16:44:54+00:00July 20, 2022|Uncategorized|Comments Off on Erythromycin

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