Drug Information

  


      












Pharmacokinetics

It is absorbed
moderately well from the gastro-intestinal tract. It is a potent and
highly selective serotonin (5HT) uptake inhibitor . It has no affinity
for adrenoreceptors, histamine, GABA ‘B’ or muscarinic receptors.




Top

    

Indication
& Dosage


 

Oral

ALL TYPES OF DEPRESSION WHERE SEDATIONIS NOT REQUIRED,
OBSESSIVE-COMPULSIVE DISORDERS BULMIAM NARCOLEPSY, CATALEPSY:
Start with
20mg o.d in the mornings. Increase at 20mg/day upto maximum of 80mg/day
in 2 divided doses. elderly: Reduce dosage. Children: Not recommended.

Top

  
 

Action




Potent and highly selective
inhibitor of reuptake of serotonin (5 HT). No affinity for adrenoceptors
or histaminem GBA ‘B’ or muscarinic receptors.

Top

  
 

Interaction

Anticoagulants,
digitalis glycosides : Varying blood levels of these drugs or fluoxetine
may occur. Central nervous system (CNS) depressants : The CNS depressant
effects may be potentiated. Monoamine oxidase (MAO) inhibitors : Taking
fluoxetine while taking or within 2 weeks of taking MAO inhibitors may
cause confusion, agitation, restlessness, stomach or intestinal
symptoms, sudden hyperpyrexia, severe hypertension, and severe
convulsions; at least 14 days should be allowed between stopping
treatment with an MAO inhibitor and starting treatment with fluoxetine;
if the patient has been taking fluoxetine, at least 5 weeks should be
allowed before starting treatment with an MAO inhibitor. Phenytoin :
Taking this drug with fluoxetine may result in higher blood levels of
phenytoin, which increases the chance of serious side effects.
Tryptophan: Taking this drug with fluoxetine may result in increased
agitation or restlessness and stomach or intestinal problems.

Top

  
 

Adverse
Effect & Precaution




Drowsiness, skin rash,
insomnia, anxiety, weakness, fatigue, nausea, anorexia, epigastirc
distress, diarrhoea, tremor and sweating.

 
 


Precautions to be taken in patients
with epilepsy, liver failure, cardiac disease, diabetes and in
pregnancy.


Pregnancy: Safety not
established.

Breast Feeding: Contraindicated.

Man: May be given in reduced dose.
 

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Brands
available in market


 


















































 


DAWNEX


Micro Labs


CAPS


20mg


10


11.95


FLUDAC


Alidac


CAPS


20mg


10


23.10


SUSP


20mg/ml


60ml


29.00


FLUFRAN


Unique


CAPS


20mg


10


25.00


FLUGEN


LA Pharma


CAPS


20mg


10


18.00


FLUMEG


Umedica


CAPS


20mg


10


25.00


FLUNAT


Natco


TAB


20mg


10


20.00


FLUNIL


Intas


CAPS


10mg


10


10.25


CAPS


20mg


10


22.25


FLUPAR


Medja


TAB


20mg


10


13.00


FLURON


Kamron


CAPS


20mg


10


12.00


FLUTINOL


Sun Pharma


CAPS


20mg


10


27.00


FLUXAL


Albert David


CAPS


20mg


10


18.80


LOFTIL


SPPL


CAPS


20mg


10


22.69


NODEP


Pace(SOL)


CAPS


20mg


10


26.75


NUZAC


Protec


CAPS


20mg


10


20.20


OXEDEP


Torrent


CAP


20mg


10


23.50


PERSONA


Yash


CAPS


20mg


10X10


198.90


PLATIN


Merind


CAPS


20mg


10


35.00


CAPS


10mg


14


19.30


PRODAC


RPG


CAPS


20mg


10


23.21


PRODEP


Sun Pharma


CAPS


20mg


10


25.00


TRIZAC


Unisearch


CAPS


20mg


10


23.00


Top

  
 



 






 

   

   
Drug Information
  

      

Pharmacokinetics

It is absorbed moderately well from the gastro-intestinal tract. It is a potent and highly selective serotonin (5HT) uptake inhibitor . It has no affinity for adrenoreceptors, histamine, GABA ‘B’ or muscarinic receptors.


Top
    

Indication & Dosage
 
Oral
ALL TYPES OF DEPRESSION WHERE SEDATIONIS NOT REQUIRED, OBSESSIVE-COMPULSIVE DISORDERS BULMIAM NARCOLEPSY, CATALEPSY:
Start with 20mg o.d in the mornings. Increase at 20mg/day upto maximum of 80mg/day in 2 divided doses. elderly: Reduce dosage. Children: Not recommended.

Top
    

Action

Potent and highly selective inhibitor of reuptake of serotonin (5 HT). No affinity for adrenoceptors or histaminem GBA ‘B’ or muscarinic receptors.

Top
    

Interaction

Anticoagulants, digitalis glycosides : Varying blood levels of these drugs or fluoxetine may occur. Central nervous system (CNS) depressants : The CNS depressant effects may be potentiated. Monoamine oxidase (MAO) inhibitors : Taking fluoxetine while taking or within 2 weeks of taking MAO inhibitors may cause confusion, agitation, restlessness, stomach or intestinal symptoms, sudden hyperpyrexia, severe hypertension, and severe convulsions; at least 14 days should be allowed between stopping treatment with an MAO inhibitor and starting treatment with fluoxetine; if the patient has been taking fluoxetine, at least 5 weeks should be allowed before starting treatment with an MAO inhibitor. Phenytoin : Taking this drug with fluoxetine may result in higher blood levels of phenytoin, which increases the chance of serious side effects. Tryptophan: Taking this drug with fluoxetine may result in increased agitation or restlessness and stomach or intestinal problems.

Top
    

Adverse Effect & Precaution

Drowsiness, skin rash, insomnia, anxiety, weakness, fatigue, nausea, anorexia, epigastirc distress, diarrhoea, tremor and sweating.
 
 
Precautions to be taken in patients with epilepsy, liver failure, cardiac disease, diabetes and in pregnancy.
Pregnancy: Safety not established.
Breast Feeding: Contraindicated.
Man: May be given in reduced dose.
 

Top
    

 

DAWNEX

Micro Labs

CAPS

20mg

10

11.95

FLUDAC

Alidac

CAPS

20mg

10

23.10

SUSP

20mg/ml

60ml

29.00

FLUFRAN

Unique

CAPS

20mg

10

25.00

FLUGEN

LA Pharma

CAPS

20mg

10

18.00

FLUMEG

Umedica

CAPS

20mg

10

25.00

FLUNAT

Natco

TAB

20mg

10

20.00

FLUNIL

Intas

CAPS

10mg

10

10.25

CAPS

20mg

10

22.25

FLUPAR

Medja

TAB

20mg

10

13.00

FLURON

Kamron

CAPS

20mg

10

12.00

FLUTINOL

Sun Pharma

CAPS

20mg

10

27.00

FLUXAL

Albert David

CAPS

20mg

10

18.80

LOFTIL

SPPL

CAPS

20mg

10

22.69

NODEP

Pace(SOL)

CAPS

20mg

10

26.75

NUZAC

Protec

CAPS

20mg

10

20.20

OXEDEP

Torrent

CAP

20mg

10

23.50

PERSONA

Yash

CAPS

20mg

10X10

198.90

PLATIN

Merind

CAPS

20mg

10

35.00

CAPS

10mg

14

19.30

PRODAC

RPG

CAPS

20mg

10

23.21

PRODEP

Sun Pharma

CAPS

20mg

10

25.00

TRIZAC

Unisearch

CAPS

20mg

10

23.00

Top
    

 

 

By |2022-07-20T16:43:06+00:00July 20, 2022|Uncategorized|Comments Off on Fluoxetine

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