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Drug Information
Pharmacokinetics
| Indication
& Dosage | Action
| Interaction
Adverse
Effect & Precautions |
Brands available in Market
Pharmacokinetics
It is inactive when given
orally and has short plasma half life. It is extensively degraded in
liver, kidney and plasma.
Indication
& Dosage
SC/IM/IV
HYPOGLYCEMIA: Adults: 0.5-1 unit (mg); if no response within 15min, IV
glucose must be given. Children: Same as above.
AS A DIAGNOSTIC AID IN THE RADIOLOGIC EXAMINATION OF GIT: 0.5-2 units
IM/IV ABOUT 10 min prior to initiation of procedure. See mfg lit.
Action
A polypeptide hormone of alpha cells of islets of Langerhans, it
increases plasma-glucose concentration by mobilising hepatic glycogen.
It can be injected SC/IM/IV. It has positive inotropic and chronotropic
action on cardia which is not antagonised by beta-blockers. (May be
useful in beta-blocker poisoning). It relaxes gut and inhibits secretion
of gastric acid.
Anticoagulants, oral / 
Effect of anticoagulants by
hypoprothrombinemia
Adverse
Effect & Precaution
Nausea, vomiting, allergic
reactions including urticaria, respiratory distress and hypotension.
Precaution: Blood glucose estimation should be done till recovery.
Pregnancy: Use with caution.
Breast Feeding: Use with caution.
