Drug Information

  





Glycopyrrolate



 












 

Indication
& Dosage

 


IM/IV

PREANESTHETIC MEDICATION:
Adults:200-400mcg(4-5mcg/kg to a max of
400mcg) IM OR IV injection. Children: 4-8mcg/kg to a max of 200mcg IM or
IV injection.

INTRAOPEATIVE MEDICATION: Same dose as above by IV INJECTION FOR CONTORL
OF MUSCARINIC SIDE EFFECTS OF NEOSTIGMINE IN REVERSAL OF COMPETETIVE
NEUROMUSCULAR BLOCK: Adult: By IV injection 10-15mcg/kg with every
50mcg/kg neostigmine. Children: 10mcg/kg with every 50mcg/kg neostigmine.

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Action

It is a synthetic muscarinic
rceptor antagonist. It induces smooth muscle relazation; it reduces
volume & free acidity of gastric secretions & controls
pharyngeal. tracheal & bronchial secretions. It antagonizes
muscarinic symptoms (bronchorrhea, bronchopasm, bradycardia, &
intestinal hypermotility) induced by antichholinesterases. It does not
cross the blood-brain barrier.

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Interaction

 

Cycolpropane:
Increased ventricular arrhythmias.

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Adverse
Effect & Precaution



G.I. upset,
difficulty in micturation, impaired alertness, skin reactions, atropine
like effect.



Precaution: Hypertension, cardiac diseases, renal or hepatic impairment,
hyperthyroidism, high ambient temperature, intestinal obstruction.

Pregnancy: Caution, use only if clearly indicated.

Breast Feeding: Contraindicated.

Man: May be given in reduced dose.

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Brands
available in market

 











 



GLYCOPYRROLATE


Khandelwal


INJ


0.2mg/ml


1ml


7.00


PYROLATE


Neon Labs


INJ


0.2mg/ml


10x1ml


81.00


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Drug Information
  


Glycopyrrolate
 

 
Indication & Dosage
 

IM/IV
PREANESTHETIC MEDICATION:
Adults:200-400mcg(4-5mcg/kg to a max of 400mcg) IM OR IV injection. Children: 4-8mcg/kg to a max of 200mcg IM or IV injection.
INTRAOPEATIVE MEDICATION: Same dose as above by IV INJECTION FOR CONTORL OF MUSCARINIC SIDE EFFECTS OF NEOSTIGMINE IN REVERSAL OF COMPETETIVE NEUROMUSCULAR BLOCK: Adult: By IV injection 10-15mcg/kg with every 50mcg/kg neostigmine. Children: 10mcg/kg with every 50mcg/kg neostigmine.

TOP
 

Action

It is a synthetic muscarinic rceptor antagonist. It induces smooth muscle relazation; it reduces volume & free acidity of gastric secretions & controls pharyngeal. tracheal & bronchial secretions. It antagonizes muscarinic symptoms (bronchorrhea, bronchopasm, bradycardia, & intestinal hypermotility) induced by antichholinesterases. It does not cross the blood-brain barrier.

TOP
 

Interaction
 
Cycolpropane: Increased ventricular arrhythmias.

 TOP
    

Adverse Effect & Precaution

G.I. upset, difficulty in micturation, impaired alertness, skin reactions, atropine like effect.

Precaution: Hypertension, cardiac diseases, renal or hepatic impairment, hyperthyroidism, high ambient temperature, intestinal obstruction.
Pregnancy: Caution, use only if clearly indicated.
Breast Feeding: Contraindicated.
Man: May be given in reduced dose.

TOP
 
    

Brands available in market
 

 

GLYCOPYRROLATE

Khandelwal

INJ

0.2mg/ml

1ml

7.00

PYROLATE

Neon Labs

INJ

0.2mg/ml

10x1ml

81.00

 TOP
 

 

 

By |2022-07-20T16:43:00+00:00July 20, 2022|Uncategorized|Comments Off on Glycopyrrolate

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