Drug Information

  


    



Iodine



       










 

Pharmacokinetics



Well absorbed after oral
administration, it crosses placenta.


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Indication
& Dosage






Oral

PREPARATIONOF HYPERTHYROID PATIENTS FOR SURGERY:
(8mg iodine/5ml soln)
Give 5-10ml t.i.d well diluted in milk or water, consecutively ofr 10-14
days prior to surgery, along wit hantithyroid drugs.


TREATMENT OF THYROID CRISIS:
Pot.Iodide oral or nasogastric route 50-100mg
b.i.d. Stop after 10 days and maintain on antithyroid drugs.


PROPHYLAXIS IN ENDEMIC GOITRE AREA:
20mg of pot.iodide/kg of salt.


PREVENTION OF RADIACTIVE IODINE UPTAKE BY THYROID:
With the use of
radioactive iodine-labelled albumin or fibronogen, a substantial part of
iodine is taken up by thyroid. 30mg of pot.iodide as a single dose
followed by 15mg daily for 7 days or more can prevent the radio-iodine
uptake by thyroid.

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Action


 

Iodine’s important aciton is inhibition of thyroid hormone
release-Thyroid constipation. Despitge the fact that ioidine is a
constituent of thyroxine, it is a rapidly acting thyroid inhibitor. when
ingested, It is reduced in the intestine to iodide and the response to
iodine or iodides is essentially identical. Enlarged thyroid gland shrinks
in size and becomes less friable, firm and less vascular. With daily
administration, peak effects are observed in about 10-15 days, beyond
which “thyroid escape” occurs, and thyrotoxicosis may return
with greater severtiy.

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Adverse
Effect & Precautions




Angiodema,
fever, thrombocytopenia, arthralgia, lymphadenopathy, salivation,
sneezing, petichael haemorrhages and swelling of lips and eyelids.



Precaution: ONchronic use with high dose may cause goiter and
hypothroidism. Acne may flare.

Pregnancy: Contraindicated

Breast Feeding: Contraindicated.

Man: Use with caution.


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Brands available in market :








COLLOSOL


Duphar-Interfan


LIQUID


8mg/5ml


100ml


17.06









Top




    


  



 






 

         

  
Drug Information
  

    
Iodine
       

 
Pharmacokinetics

Well absorbed after oral administration, it crosses placenta.

Top
  

Indication & Dosage

Oral
PREPARATIONOF HYPERTHYROID PATIENTS FOR SURGERY:
(8mg iodine/5ml soln) Give 5-10ml t.i.d well diluted in milk or water, consecutively ofr 10-14 days prior to surgery, along wit hantithyroid drugs.
TREATMENT OF THYROID CRISIS: Pot.Iodide oral or nasogastric route 50-100mg b.i.d. Stop after 10 days and maintain on antithyroid drugs.
PROPHYLAXIS IN ENDEMIC GOITRE AREA: 20mg of pot.iodide/kg of salt.
PREVENTION OF RADIACTIVE IODINE UPTAKE BY THYROID: With the use of radioactive iodine-labelled albumin or fibronogen, a substantial part of iodine is taken up by thyroid. 30mg of pot.iodide as a single dose followed by 15mg daily for 7 days or more can prevent the radio-iodine uptake by thyroid.

Top
  

Action
 
Iodine’s important aciton is inhibition of thyroid hormone release-Thyroid constipation. Despitge the fact that ioidine is a constituent of thyroxine, it is a rapidly acting thyroid inhibitor. when ingested, It is reduced in the intestine to iodide and the response to iodine or iodides is essentially identical. Enlarged thyroid gland shrinks in size and becomes less friable, firm and less vascular. With daily administration, peak effects are observed in about 10-15 days, beyond which “thyroid escape” occurs, and thyrotoxicosis may return with greater severtiy.

Top
   

Adverse Effect & Precautions

Angiodema, fever, thrombocytopenia, arthralgia, lymphadenopathy, salivation, sneezing, petichael haemorrhages and swelling of lips and eyelids.

Precaution: ONchronic use with high dose may cause goiter and hypothroidism. Acne may flare.
Pregnancy: Contraindicated
Breast Feeding: Contraindicated.
Man: Use with caution.

Top
  

 
Brands available in market :

COLLOSOL

Duphar-Interfan

LIQUID

8mg/5ml

100ml

17.06


Top
    
  

 

 

By |2022-07-20T16:43:14+00:00July 20, 2022|Uncategorized|Comments Off on Iodine

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