Drug Information

   


         











Pharmacokinetics



It is completely absorbed
with an oral bioavaiability of 89%. Plasma binding exceeds 99.5%. Total
plasma clearance was 0.42 to 0.48 I/h. Dual excretion was observed in
urine and faeces. Food intake had no impact on the pharmacokinetics of
the drug.

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Indication
& Dosage








IM/IV/Oral/Rectal

RHEUMATOID ARTHRITIS, OSTEOARTHRITIS: Adults: 7.5mg-15mg OD.

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Action


Meloxicam is a new NSAID of the oxicam class. it differs from other
NSAIDS in that it has a greater selective inhibitory activity against
the inducible isoform of cyclo oxygenase (COX-2) than against the COX-1,
which is associated with gastrointestinal/renal adverse effect and
inhibition of platelet aggregation effects of the NSAIDS.

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Interactions



Cimetidine, aluminium/magnesium
hydroxide antacid or aspiring: Concomitant use did nt significantly
affect the pharmacokinetic profile of meloxicam.



Frusemide or digoxin: Meloxicam did not affect the pharmacokinetics
inshort time studies.

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Precaution



Peptic ulcer

Pregnancy: Contraindicated.

Breast Feeding: Contraindicated

Man: Use with caution

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Brand
available in market
























ARTAZ

Foreva
TAB 15mg 10 13.52
TAB 7.5mg 10 8.77
M-CAM

Unichem
TAB 7.5mg

0.00
TAB 15mg

0.00
TAB 7.5mg

0.00
MEL-OD

Zydus Cadila
TAB 15mg 10 17.00
TAB 7.5mg 10 9.50
MELOSUGANRIL

SPPL
TAB 15mg 10 17.00
TAB 7.5mg 10 9.90
MUVERA

Sun
TAB 15mg 10 17.00
TAB 15mg 10 17.00
RAFREE

Dr.Reddy’s
TAB 15mg 10 17.10
TAB 7.5mg 10 9.90





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Drug Information
   

         

Pharmacokinetics

It is completely absorbed with an oral bioavaiability of 89%. Plasma binding exceeds 99.5%. Total plasma clearance was 0.42 to 0.48 I/h. Dual excretion was observed in urine and faeces. Food intake had no impact on the pharmacokinetics of the drug.

TOP
   

Indication & Dosage

IM/IV/Oral/Rectal
RHEUMATOID ARTHRITIS, OSTEOARTHRITIS: Adults: 7.5mg-15mg OD.

TOP
   

Action
Meloxicam is a new NSAID of the oxicam class. it differs from other NSAIDS in that it has a greater selective inhibitory activity against the inducible isoform of cyclo oxygenase (COX-2) than against the COX-1, which is associated with gastrointestinal/renal adverse effect and inhibition of platelet aggregation effects of the NSAIDS.

TOP
   

Interactions

Cimetidine, aluminium/magnesium hydroxide antacid or aspiring: Concomitant use did nt significantly affect the pharmacokinetic profile of meloxicam.

Frusemide or digoxin: Meloxicam did not affect the pharmacokinetics inshort time studies.

TOP
 

Precaution

Peptic ulcer
Pregnancy: Contraindicated.
Breast Feeding: Contraindicated
Man: Use with caution

TOP
    

ARTAZ

Foreva

TAB

15mg

10

13.52

TAB

7.5mg

10

8.77

M-CAM

Unichem

TAB

7.5mg

0.00

TAB

15mg

0.00

TAB

7.5mg

0.00

MEL-OD

Zydus Cadila

TAB

15mg

10

17.00

TAB

7.5mg

10

9.50

MELOSUGANRIL

SPPL

TAB

15mg

10

17.00

TAB

7.5mg

10

9.90

MUVERA

Sun

TAB

15mg

10

17.00

TAB

15mg

10

17.00

RAFREE

Dr.Reddy’s

TAB

15mg

10

17.10

TAB

7.5mg

10

9.90

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By |2022-07-20T16:42:54+00:00July 20, 2022|Uncategorized|Comments Off on Meloxicam

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