Drug Information

 


    











 

Pharmacokinetics

 

It is rapidly absorbed form the GI tract, metabolised in teh liver and
excreted in urine as the glucurionide and sulphate conjugates of its
metabolites. Small amount is excreted in faeces.

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Indication
& Dosage






Oral

PAINFUL SKELETAL MUSCLE SPASM ASSOCIATED WTIH MUSCULO-SKELETAL
DISORDERS:
Upto 1.5g q.i.d. reduced to maintenance dose of 1g
q.i.d.
Elderly: Lower doses starting at 250mg t.i.d.




IV

ACUTE SKELETAL MUSCLE SPASM VIOLENT SPASM I TETANUS:
2-3g IV over 15
mins followed by 2g IV every 6 hrs. 

Children: Tetanus: 15mg/kg.

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Action

  

Methocarbamol is a centrally acting skeletal muscle relaxant whose
precise mode action is not known. It would cause general depression of
nervous system

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Interactions

 


Alcohol and other CNS depressant durgs: CNS depressant effects
potentiated. Anoretics and anticholinergics: Efficay increased by
methocarbamol.

Lab Tests: Causes colour interference in certain screening tests for
5-hydroxy-indoleacetic acid(SHIAA) and Vanillyl mandelic acid (VMA).

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Adverse
Effect & Precaution




Nausea,anoxeria, skin rash, vertigo, drowsiness, headache, fever.



Precaution: Impairment of hepatic or renal fucntion.

Pregnancy: Use with caution.

Breast Feeding: Use with caution.

Man: May be used in reduced dose.

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Brand
available in market


 










ROBINAX

Khandelwal

INJ

100mg/ml

10ml

15.00

TAB

500mg

10

30.03




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Drug Information
 

    

 
Pharmacokinetics
 
It is rapidly absorbed form the GI tract, metabolised in teh liver and excreted in urine as the glucurionide and sulphate conjugates of its metabolites. Small amount is excreted in faeces.

TOP
  

Indication & Dosage

Oral
PAINFUL SKELETAL MUSCLE SPASM ASSOCIATED WTIH MUSCULO-SKELETAL DISORDERS:
Upto 1.5g q.i.d. reduced to maintenance dose of 1g q.i.d. Elderly: Lower doses starting at 250mg t.i.d.

IV
ACUTE SKELETAL MUSCLE SPASM VIOLENT SPASM I TETANUS:
2-3g IV over 15 mins followed by 2g IV every 6 hrs. 
Children: Tetanus: 15mg/kg.

TOP
  

Action
  
Methocarbamol is a centrally acting skeletal muscle relaxant whose precise mode action is not known. It would cause general depression of nervous system

TOP
    

Interactions
 

Alcohol and other CNS depressant durgs: CNS depressant effects potentiated. Anoretics and anticholinergics: Efficay increased by methocarbamol.
Lab Tests: Causes colour interference in certain screening tests for 5-hydroxy-indoleacetic acid(SHIAA) and Vanillyl mandelic acid (VMA).

TOP
   

Adverse Effect & Precaution

Nausea,anoxeria, skin rash, vertigo, drowsiness, headache, fever.

Precaution: Impairment of hepatic or renal fucntion.
Pregnancy: Use with caution.
Breast Feeding: Use with caution.
Man: May be used in reduced dose.

TOP
   

ROBINAX

Khandelwal

INJ

100mg/ml

10ml

15.00

TAB

500mg

10

30.03

TOP

                                                     
                                               

 

By |2022-07-20T16:41:38+00:00July 20, 2022|Uncategorized|Comments Off on Methocarbamol

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