|
Drug Information
Pharmacokinetics
| Indication
& Dosage | Action
| Interacations |
Precautions
|
Brands available in Market
Pharmacokinetics
It is absorbed after oral administration from the gastro-intestinal
tract. When given orally Miconazole is metabolised in the liver. It can
also be given intrathecally.Single application on skin acts for a few
days .
Indication
& Dosage
Topical Skin
FUNGAL SKIN CONDITION: (2% cream) Apply twice daily for 2 weeks Rub
gently. Longer treatment may be necessary.
Action
At low doses miconazole inhibits ergosterol synthesis which results
in disturbance of cell membrane functions. At high concentrations causes
direct membrance damage. Effective against several fungal pathogens
including Trichophyton, Microsporum and Epidermophyton; Candida albicans,
Cryptococcus neoformans, Cocciodes and paracoccioides.
Interactions
Few interactions have been reported.
Adverse
Effect & Precaution
Burning sensation, local irritation, contact dermatitis.
Alcohol abuse or Hepatic disease may increase the
chance of adverse effects caused by azole antifungals.It may cause
vaginal irritation.
Pregnancy: Use with caution.
Breast Feeding: Use with caution.
Man: May be used.
CANDISTAT
Merck
CREAM
2% w/w
15g
14.18
DAKTARIN
Ethnor
POWDER
2%
10g
18.53
GEL
2%
20g
30.95
SOLN
2%
10ml
19.35
FUNGITOP
Micro Labs
GEL
2%
15g
25.00
GYNO-DAKTARIN
Ethnor
GEL
2%w/w
20gm
28.60
GEL
2%
50gm
46.70
MICODOL
Dolphin
OINT
2%
15g
14.50
MICOGEL
Cipla
CREAM
2%
15g
15.50
ZOLE
Rexcel
OINT
2%
15g
21.00
LOTION
2%
15ml
20.95
POWDER
2%
15g
18.50
