Drug Information

   

     















Pharmacokinetics


Readily absorbed from the GI
tract, widely distributed in body tissues and fluids including the CSF
and metabolised in liver. It is excreted mainly in the urine as
conjugates and metabolites and to a lesser extent in faeces.

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Indication
& Dosage




Oral

BACTERIAL VAGINOSIS:
1.5g single dose for one day. Alternatively, 500mg
ODX5-7 days can also be used.

ANAEROBIC BACTERIAL INFECTIONS: 500mg b.i.d.x5-10 days.

Parenteral

ANAEROBIC BACTERIAL INFECTIONS:
Treatment: Initially IV INFUSION OF 0.5
1G, FOLLOWED by 0.5g every 12hrs x 5-10 days; oral therapy substituted
at the earliest opportunity. In children, 10mg/kg every 12 hrs. Surgical
prophylaxis: 1g given by IV infusion 30 min prior to surgical procedure.

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Action




Omnidazole is active against protozoa and anaerobic bacteria and is
used like metronidazole in the management in the mangement of
susceptible protozoal anaerobic bacterial infections. Ornidazole’s
longer half-life(12-14 hrs) in comparison to that of metronidazole (6-8
hrs) os of particular advantage, for it favorably reduces the dosage
frequency and duration of therpay in many of the relevant clinical
infections.

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Interaction

 

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Adverse Effect &
Precautions




Nausea, abdominal pain,
vertigo, skin rash, headache.

Precaution: Ataxia, vertigo, metal confusion.

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Brands
available in market














DAZOLIC

Sun Pharma

TAB

500mg

10

45.00

INF

0.5g/100ml

VIAL

27.50


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Drug Information
   

     

Pharmacokinetics

Readily absorbed from the GI tract, widely distributed in body tissues and fluids including the CSF and metabolised in liver. It is excreted mainly in the urine as conjugates and metabolites and to a lesser extent in faeces.

TOP
    

Indication & Dosage

Oral
BACTERIAL VAGINOSIS:
1.5g single dose for one day. Alternatively, 500mg ODX5-7 days can also be used.
ANAEROBIC BACTERIAL INFECTIONS: 500mg b.i.d.x5-10 days.

Parenteral
ANAEROBIC BACTERIAL INFECTIONS:
Treatment: Initially IV INFUSION OF 0.5 1G, FOLLOWED by 0.5g every 12hrs x 5-10 days; oral therapy substituted at the earliest opportunity. In children, 10mg/kg every 12 hrs. Surgical prophylaxis: 1g given by IV infusion 30 min prior to surgical procedure.

TOP
    

Action

Omnidazole is active against protozoa and anaerobic bacteria and is used like metronidazole in the management in the mangement of susceptible protozoal anaerobic bacterial infections. Ornidazole’s longer half-life(12-14 hrs) in comparison to that of metronidazole (6-8 hrs) os of particular advantage, for it favorably reduces the dosage frequency and duration of therpay in many of the relevant clinical infections.

TOP
    

Interaction

 

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Adverse Effect & Precautions

Nausea, abdominal pain, vertigo, skin rash, headache.
Precaution: Ataxia, vertigo, metal confusion.

TOP
    

DAZOLIC

Sun Pharma

TAB

500mg

10

45.00

INF

0.5g/100ml

VIAL

27.50

TOP
    

                                                         

By |2022-07-20T16:44:59+00:00July 20, 2022|Uncategorized|Comments Off on Ornidazole

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