Drug Information

   


    











Pharmacokinetics


It is a analogue of Xanthine, it increases the deformability of RBC,
thereby allowing the RBC to migrate through the capillaries more easily,
thus improving the circulation through the blood vessels.

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Indication
& Dosage


Oral

PERIPHERAL VASCULAR DISEASES EVIDENT AS INTERMITTENT CLAUDICATION,
TROPHIC LEG ULCERS, CEREBROVASCULAR DISEASE, RETINAL VASCULAR DISORDERS,
DIABETIC VASCULAR DISORDERS, ISCHAEMIC HEART DISEASE: 400MG 2-3 times
daily with meals minimum 8 weeks for optimum effects.

IV Infusion

INDICATIONS AS ABOVE OF SEVERE TYPE: 0.6mg/kg/hr. Not to exceed 1200mg
in 24 hour.

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Action



Pentoxyfilline reduces blood viscosity and improves microcirulation and
tissue oxygentation. Erythrocytes become more flexiable and can squeeze
through narrower channels.

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Interaction

Smoking tobacco may worsen the condition since
nicotine may further enhance the blockage of the blood vessels.

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Precautions






Vertigo, nausea, vomiting, flushing, dyspepsia

Precuations should be taken when administering
Pentoxifylline with other anti-coagulants or if nicotine is being used
by the patient.

Pregnancy: Contraindicated.

Breast Feeding: Contraindicated.

Man: Use with caution.

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Brands
available in market
























FLEXITAL

Sun Pharma
TAB 400mg 10 23.50
INJ 20mg/ml 15ml 5.42
FLOWPENT

Knoll Pharma
TAB 400mg/ml 10 58.10
INJ 20mg/ml 15ml 10.95
KINETAL

Protec
TAB 400mg 10 23.93
INJ 20mg/ml 15ml 5.51
PENTOFYL

Pace(SOL)
TAB 400mg 10 59.00
RBFLEX

Pace(SOL)
SR-TAB 400mg 10 55.50
INJ 20mg/ml 15ml 10.90
TRENTAL

Hoechst Marion Roussel
INJ 300mg 5x15ml 28.39
SR-DRA 400mg 10 25.76




Top

 







 

     

    
Drug Information
   

    

Pharmacokinetics

It is a analogue of Xanthine, it increases the deformability of RBC, thereby allowing the RBC to migrate through the capillaries more easily, thus improving the circulation through the blood vessels.

Top
  

Indication & Dosage
Oral
PERIPHERAL VASCULAR DISEASES EVIDENT AS INTERMITTENT CLAUDICATION, TROPHIC LEG ULCERS, CEREBROVASCULAR DISEASE, RETINAL VASCULAR DISORDERS, DIABETIC VASCULAR DISORDERS, ISCHAEMIC HEART DISEASE: 400MG 2-3 times daily with meals minimum 8 weeks for optimum effects.

IV Infusion
INDICATIONS AS ABOVE OF SEVERE TYPE: 0.6mg/kg/hr. Not to exceed 1200mg in 24 hour.

Top
  

Action

Pentoxyfilline reduces blood viscosity and improves microcirulation and tissue oxygentation. Erythrocytes become more flexiable and can squeeze through narrower channels.

Top
  

Interaction

Smoking tobacco may worsen the condition since nicotine may further enhance the blockage of the blood vessels.

Top
  

Precautions

Vertigo, nausea, vomiting, flushing, dyspepsia
Precuations should be taken when administering Pentoxifylline with other anti-coagulants or if nicotine is being used by the patient.
Pregnancy: Contraindicated.
Breast Feeding: Contraindicated.
Man: Use with caution.

Top
  

FLEXITAL

Sun Pharma

TAB

400mg

10

23.50

INJ

20mg/ml

15ml

5.42

FLOWPENT

Knoll Pharma

TAB

400mg/ml

10

58.10

INJ

20mg/ml

15ml

10.95

KINETAL

Protec

TAB

400mg

10

23.93

INJ

20mg/ml

15ml

5.51

PENTOFYL

Pace(SOL)

TAB

400mg

10

59.00

RBFLEX

Pace(SOL)

SR-TAB

400mg

10

55.50

INJ

20mg/ml

15ml

10.90

TRENTAL

Hoechst Marion Roussel

INJ

300mg

5x15ml

28.39

SR-DRA

400mg

10

25.76

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By |2022-07-20T16:42:50+00:00July 20, 2022|Uncategorized|Comments Off on Pentoxifylline

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