Phenazopyridine

Pharmacokinetics

Phenazopyridine hydrochloride is
absorbed from the gastrointestinal tract. It is excreted mainly in the
urine; up to 65% may be excreted as unchanged phenazopyridine and 18% as
paracetamol.

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Indication
& Dosage

 

Oral

FOR SYMPTOMATIC RELIEF OF PAIN BURNING, URGENCY, FREQUENCY AND OTHER
DISCOMFORTS ARISING FROM IRRITATION OF THE LOWER URINARY TRACT MUCOSA
CAUSED BY INFECTION, TRAUMA, SURGERY, ENDOSCOPIC PROCEDURES, OR PASSAGE
OF SOUND OR CATHETERS: ADULTS: 200mg t.i.d after food. When used with an
antibacterial agent for UTI; phenazopyridine dose duration should not
exceed 2 days.

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Action



It is an azo dye that exerts a urinary tract analgesic effect. After
oral administration, the drug is excreted in the urine where it exterts
a topical analgesic effect on the mucosa of the urinary tract. This
action helps to relieve pain, burning, urgency & frequency
associated cystitis, prostatitis & urethritis.

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Interaction

Lab test: May interfere with urinalysis based on
spectrometry or color reactions.

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Adverse Effect & Precautions






Nausea, abdominal discomfort, jaundice, haemolytic anaemia,
methaemoglobinaemia.



Long term use should be avoided. The urine colour turns orange red which
is harmless

Pregnancy: Use only if clearly needed.

Breast Feeding: Use with caution.

Man: Use with caution.

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Brands
available in market

 

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