Drug
Information


   

     












 Pharmacokinetics.

 

Salbutamol is chemically related to isoprenaline. It
is not metabolised by COMT and MAO, therefore the action of the drug
lasts longer than isoprenaline. It acts by stimulating the Beta-2
receptor cells of the smooth muscles in the bronchioles and uterus. It
has minimal cardiac stimulant effect and does not cause hypertension.

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Indication
& Dosage


 



Oral

BRONCHOSPASM IN PATIENTS WITH REVERSIBLE OBSTRUCTIVE AIRWAY DISEASE:

Adults:2-4mg three or four times a day. Extended release tablets 4-8mg
b.i.d. Children: 2mg three or four time a day.



Inhalation

BRONCHOSPASM IN PATIENTS WITH REVERSIBLE OBSTRUCTIVE AIRWAY DISEASE:
Adult : 100-200mcg Aerosol three or four times a day or 200-400mcg
Rotacaps dry powder three or four times a day or 2.5mg nebuliser
solution three or four times a day. Children (6-12 yrs) 100mcg Aerosol
or 200mcg Rotacaps dry powder three or four times a day.

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Action



Primary action of salbutamol is to stimulate adenyl cyclase which
catalyzes the formation of cyclic AMP. The cyclic AMP thus formed
mediates smooth muscle relaxation and bronchodilation.

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Interaction

It may interact with sympathomimetic bronchodilators.
Use with Diuretics and Xanthines may augument hypokalemia.

 


Precautions

Precautions must be taken when taking the drug during
pregnancy, lactation and in the elderly.

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Brands
available in market








































ASMANILINGA

Inga
TAB 2mg 10 1.26
TAB 4mg 10 2.01
ASTHALIN

Cipla
TAB 2mg 10 3.45
TAB 4mg 10 5.21
SA-TAB 4mg 10 6.05
SA-TAB 8mg 10 9.00
SYRUP 2mg/5ml 100ml 11.21
INHALER 100mcg/md 200(md) 67.07
ASTHALIN RESPIRATOR

Cipla
SOLN 5mg/ml 15ml 15.59
ASTHALIN ROTACAPS ROTAHEALER

Cipla
ROTACAPS 200mcg 30 39.97
BRONKOTAB

Biddle Sawyer
TAB 2mg 10 2.24
BRONLOTAB 4 EX

Raptakos
TAB 4mg 10 4.72
DURASAL-CR

Raptakos
CR-CAPS 8mg 10 9.14
GLAXO SALBUTAMOL INH

Glaxo Pharma
INHAL 100mcg/inh 200INH 82.91
SALBU

Pharmacia & Upjohn
CAPS 4mg 10 7.81
CAPS 8mg 10 9.18
SYRUP 2mg/5ml 100ml 16.69
SALMAPLON

Khandelwal
TAB 2mg 10 1.31
TAB 4mg 10 2.07
VENTORLIN

Glaxo Allenbury
SYRUP 2mg/5ml 100ml 8.47
CR-CAPS 4mg 10 6.52
CR-CAPS 8mg 10 9.38





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Drug Information
   

     

 Pharmacokinetics.
 
Salbutamol is chemically related to isoprenaline. It is not metabolised by COMT and MAO, therefore the action of the drug lasts longer than isoprenaline. It acts by stimulating the Beta-2 receptor cells of the smooth muscles in the bronchioles and uterus. It has minimal cardiac stimulant effect and does not cause hypertension.

TOP
     

Indication & Dosage
 
Oral
BRONCHOSPASM IN PATIENTS WITH REVERSIBLE OBSTRUCTIVE AIRWAY DISEASE:
Adults:2-4mg three or four times a day. Extended release tablets 4-8mg b.i.d. Children: 2mg three or four time a day.

Inhalation
BRONCHOSPASM IN PATIENTS WITH REVERSIBLE OBSTRUCTIVE AIRWAY DISEASE: Adult : 100-200mcg Aerosol three or four times a day or 200-400mcg Rotacaps dry powder three or four times a day or 2.5mg nebuliser solution three or four times a day. Children (6-12 yrs) 100mcg Aerosol or 200mcg Rotacaps dry powder three or four times a day.

TOP
    

Action

Primary action of salbutamol is to stimulate adenyl cyclase which catalyzes the formation of cyclic AMP. The cyclic AMP thus formed mediates smooth muscle relaxation and bronchodilation.

TOP
   

Interaction

It may interact with sympathomimetic bronchodilators. Use with Diuretics and Xanthines may augument hypokalemia.
 

Precautions

Precautions must be taken when taking the drug during pregnancy, lactation and in the elderly.

TOP
   

ASMANILINGA

Inga

TAB

2mg

10

1.26

TAB

4mg

10

2.01

ASTHALIN

Cipla

TAB

2mg

10

3.45

TAB

4mg

10

5.21

SA-TAB

4mg

10

6.05

SA-TAB

8mg

10

9.00

SYRUP

2mg/5ml

100ml

11.21

INHALER

100mcg/md

200(md)

67.07

ASTHALIN RESPIRATOR

Cipla

SOLN

5mg/ml

15ml

15.59

ASTHALIN ROTACAPS ROTAHEALER

Cipla

ROTACAPS

200mcg

30

39.97

BRONKOTAB

Biddle Sawyer

TAB

2mg

10

2.24

BRONLOTAB 4 EX

Raptakos

TAB

4mg

10

4.72

DURASAL-CR

Raptakos

CR-CAPS

8mg

10

9.14

GLAXO SALBUTAMOL INH

Glaxo Pharma

INHAL

100mcg/inh

200INH

82.91

SALBU

Pharmacia & Upjohn

CAPS

4mg

10

7.81

CAPS

8mg

10

9.18

SYRUP

2mg/5ml

100ml

16.69

SALMAPLON

Khandelwal

TAB

2mg

10

1.31

TAB

4mg

10

2.07

VENTORLIN

Glaxo Allenbury

SYRUP

2mg/5ml

100ml

8.47

CR-CAPS

4mg

10

6.52

CR-CAPS

8mg

10

9.38

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By |2022-07-20T16:41:46+00:00July 20, 2022|Uncategorized|Comments Off on Salbutamol

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