Drug Information

 


                                                          











Pharmacokinetics.

 


It given orally and is highly
concentrated in liver. It undergoes enterohepatic circulation and is
eliminated as silymarin conjugates in bile. The renal eliminations is about 
3-7%.

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Indication
& Dosage




Oral

ALCOHOLIC & TOXIC METABOLIC LIVER DISEASE: 140mg t.i.d. for 3-6
months, reducesd to 70mg t.id for maintenance.

INFECTIVE HEPATITIS: 140mg t.i.d for 4 weeks.

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Action



Acitve principle from the fruit of Silybum marianum, a mixture of
flavonolignans. Silymarin reduces the turnover of membrane phospholipids
and stabilises cell membranes of hepatocytes. Has potent antioxidant
action & prevents lipid peroxidation.

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Precautions



Pregnancy: Safety not established.

Breast Feeding: Safety not established.

Man: May be used.

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Brands
available in market


 























LEVALON

Brown & Burk
TAB 70mg 10 38.00
TAB 140mg 10 53.00
LIMARIN

Serum Institute
TAB 70mg 10 38.35
TAB 140mg 10 53.60
SILIMAR

German Remedies
CAPS 70mg 10 40.00
CAPS 140mg 10 61.20
SILYBON

Micro Labs
TAB 70mg 10 38.00
TAB 140mg 10 53.30
SIVYLAR

Ranbaxy
TAB 70mg 10 36.20
TAB 140mg 10 53.35



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Drug Information
 

                                                          

Pharmacokinetics.
 
It given orally and is highly concentrated in liver. It undergoes enterohepatic circulation and is eliminated as silymarin conjugates in bile. The renal eliminations is about  3-7%.

TOP
  

Indication & Dosage

Oral
ALCOHOLIC & TOXIC METABOLIC LIVER DISEASE: 140mg t.i.d. for 3-6 months, reducesd to 70mg t.id for maintenance.
INFECTIVE HEPATITIS: 140mg t.i.d for 4 weeks.

TOP
  

Action

Acitve principle from the fruit of Silybum marianum, a mixture of flavonolignans. Silymarin reduces the turnover of membrane phospholipids and stabilises cell membranes of hepatocytes. Has potent antioxidant action & prevents lipid peroxidation.

TOP
  

Precautions

Pregnancy: Safety not established.
Breast Feeding: Safety not established.
Man: May be used.

TOP
  

LEVALON

Brown & Burk

TAB

70mg

10

38.00

TAB

140mg

10

53.00

LIMARIN

Serum Institute

TAB

70mg

10

38.35

TAB

140mg

10

53.60

SILIMAR

German Remedies

CAPS

70mg

10

40.00

CAPS

140mg

10

61.20

SILYBON

Micro Labs

TAB

70mg

10

38.00

TAB

140mg

10

53.30

SIVYLAR

Ranbaxy

TAB

70mg

10

36.20

TAB

140mg

10

53.35

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By |2022-07-20T16:44:58+00:00July 20, 2022|Uncategorized|Comments Off on Silymarin

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