|
Drug
information
Pharmacokinetics
| Indication
& Dosage | Action
| Interactions
Adverse
Effects & Precautions |
Brands available in Market
Pharmacokinetics
Beta-blockers : These drugs reduce the effect of the adrenergic
bronchodilators. Cocaine, Ergoloid mesylates, Ergotamine, Maprotiline,
Tricyclic antidepressants : The effects of these drugs on the heart and
blood vessels may be potentiated. Digitalis glycosides : The chance of
Cardiac arrhythmias may be increased. Monoamine oxidase (MAO) inhibitors
: Using adrenergic bronchodilators when using or within 2 weeks of
taking monoamine oxidase (MAO) inhibitors may increase the effects of
MAO inhibitors
Indication
& Dosage
Oral
INFECTIONS CAUSED BY SUSCEPTIBLE ORGANISMS: 1-2g/day in four divide doses
Action
Bacteriostatic action through inhibition of protein synthesis.
Effective against a wide range of organisms including rickettsiae,
Mycoplasma pneumoniae, pathogens causing lymphogranuloma venerium and
granuloma inguinale, Borrelia recurrentis; Gram-negative organisms
including Haemophilus influenzae, H.ducreyi, Pasteurella pestis,
P.tulareniss, Bacteroides spp., Bartonella, Vibrio cholera, Brucella,
e.coli, Enterobacter, Klebsiella, Shigella; Gram-positives such as
Strep.pyogenes, Strep.faecalis, Diplococcus pneumoniae, Staph.aureus,
other pathogens such as Neisseria gonnorrhoeae, treponema pallidum,
T.pertenue (yams), Listeria monocytogenes, Clostridium, Bacillus anthracis,
Chlamydia trachomatis.
Interaction may occur with Antacids, Calcium supplements, Cholestyramine, Choline and magnesium salicylates, Colestipol, Iron-containing drugs, Laxatives, Magnesium salicylate: these drugs may decrease the potency of tetracyclines. Oral contraceptives containing estrogen: tetracyclines may decrease the contraceptive effect and increase the chance of unwanted pregnancy.
Adverse
Effect & Precautions
Anorexia,
nausea, vomiting, epigastric distress, oesophageal ulcers, skin
rash, photosensitivity, fatty liver, urtcaria, anaphylaxis,
pseudotumor cerebri, neutropenia, superinfection, tooth
discoloration.
Patients with hepatic and renal disease may
have an increased chance of adverse effects if they use
tetracycline.
Pregnancy: Contraindicated.
Breast Feeding: Contraindicated.
Man: May be used.
ACHRONYCIN
Wyeth Lederle
CAPS
250mg
10
14.70
CAPS
250mg
400
415.00
HOSTACYCLINE
Hoechst Marion Roussel
CAPS
250mg
10
10.52
CAPS
500mg
24×4
20.68
IDILIN
IDPL
CAPS
250mg
10
11.88
CAPS
500mg
4
7.16
LINEMETT
Mercury
TAB
333mg
12×10
216.00
TAB
500mg
12×10
270.00
RESTECLIN
Sarabhai
CAPS/TAB
250mg
10
14.14
CAPS/TAB
250mg
4
9.54
SUBAMYCIN
Dey’s
CAPS
250mg
10
12.78
CAPLET
500mg
4
8.15
TETRACYCLINE
Dabur
CAPS
250mg
500
490.00
CAPS
250mg
10
15.72
CAPS
250mg
1000
1427.14
THREOCYCLINE
CAPS
333mg
6
8.80
