Drug
Information





Albedazole

  
















 

Pharmacokinetics

 


Poorly
absorbed from the GI tract, oral bioavailabilty being enhanced when
given with a fatty meal (upto 5 fold). Its sulphoxide metabolite is
widely distributed throughout the body.

 

Top

   

Indication
& Dosage 

Oral : 


Hookworm Infestation Ancylostoma Duodenale necator Americanus :
A
single dose of 400mg. 

Children : Less than 10kg may be given 200mg as a single dose.




Roundworm (Ascaris lumbricoides) :
A single dose of 400mg. 




Children :
Less than 10kg may be given 200mg as a single dose. 




Threadworm (Enterobius) :
A single dose of 400mg. 




Children :
Less than 10kg may be given 200mg as a single dose.

Whipworm
(Trichuris Trichiura) :
A single dose of 400mg.




Children :
Less than 10kg may be given 200mg  as a single dose.




Tapeworm (Taenia Solium T.Saginata) :
400mg/day for 3 consecutive days.

Strongyloides
(s.stercoralis) :
400mg/day for 3 consecutive days.




Hydalid diseases (Echinococcus Granulosa) :
10mg/kg/day for 4-8 weeks.




Neurocysticercosis :
400mg b.i.d. for 30 days. 




Cutaneous Larva Migrans :
Single dose of 400mg.




Capillaria philippinensis :
400mg b.i.d for 10-20 days. 




Infestation with opisthorchis Viverrini :
400mg b.i.d for 3 days.

Top

  

Action 

Albendazole exhibits a broad spectrum anthelmintic activity
showing vermicidal, ovicidal and larvicidal action. It inhibits tubulin
polymerization in the parasite and blocks glucose uptake. Energy levels
are reduced  and death of the parasite results. Suscepitable
parasites include hookworm , roundworm, threadworm, whipworm, tapeworm,
strongyloides, opisthorchis and hydatid diseases (Echinococcus).

Top 

 

Interactions

Cimetidine /
Levels of albendazole sulfoxide in bile and cystic fluid in hydatid cyst
clients

Dexamethasone / Possible
plasma levels of albendazole sulfoxide


Praziquantel /
Plasma levels of albendazole sulfoxide


Top

 

Adverse
Effect & Precautions


 

Nausea, vomiting, epigastric distress, abnormal
LFTs, reversible alopecia.

Precaution: Hepatic and renal impairment,
in neurocysticercosis patients should be receive appropriate steroid and
anticonvulsant therapy.

Pregnancy: Contraindicated

Breast Feeding: Safety not established, use with caution

Man: May be used

Top 

  

Brand
available in Market





 


















































































































Abex

Saga labs

TAB

400mg

1

7.20

SUSP

200mg/ml

10ml

13.00

Abz

Indoco

TAB

400mg

1

11.07

SUSP

200mg/ml

10ml

12.58

Abzole

Euphoric

TAB

400mg

2

23.50

SUSP

200mg/ml

10ml

14.00

Albazole

Wings Pharma

DISP-TAB

400mg

1

12.25

SUSP

200mg/5ml

10ml

15.00

Albendol

Micro Labs

TAB

400mg

1

9.90

SUSP

200mg/5ml

10ml

14.80

Albezole

Khandelwal

TAB

400mg

1

10.96

SUSP

200mg/5ml

10ml

16.50

Albrodo

Shalaks

TAB

400mg

1

8.00

SUSP

200mg/5ml

10ml

11.15

Alminth

Torrent

TAB

200mg

2

7.90

TAB

400mg

1

12.00

SUSP

200mg/5ml

10ml

14.90

Alzad

Merind

TAB

400mg

1

12.00

SUSP

200mg/5ml

10ml

14.07

Anthel

Lincoln

CHEW-TAB

400mg

1

9.90

SUSP

200mg/5ml

10ml

12.90

Bendex

Protec

TAB

400mg

1

11.50

SUSP

200mg/5ml

10ml

14.50

Cidazole

Juggat Pharma

TAB

400mg

1

125.25

SUSP

200mg/5ml

10ml

18.00

Combantrin

Pfizer

SUSP

200mg/5ml

10ml

14.25

Combantrin A

Pifzer

TAB

400mg

1

11.21

Elminex

Cachet Pharma

TAB

400mg

1

12.25

SUSP

200mg/5ml

10ml

15.00

Elminova

Yash

TAB

400mg

20×1

212.60

SUSP

200mg/5ml

10ml

13.61

Emanthal

M.M.Labs

TAB

400mg

1

7.50

SUSP

200mg/5ml

10ml

11.30

GEKARE

Glaxo

CAPTAB

400mg

1

8.99

SUSP

200mg/5ml

10ml

11.99

Nemofex

Pharmasynth

TAB

400mg

1

10.00

SUSP

400mg/10ml

10ml

12.75

Nemozole

IPCA

SUSP

200mg/5ml

10ml

12.00

CHEW TAB

400mg

1

9.75

Neomin

Neo Pharma

Tab

400mg

1

8.00

Nopar

Malladi Drug

Tab

400mg

1

8.00

Noworm

Alkem

TAB

400mg

1

12.00

SYRUP

400mg/10ml

10ml

14.50

Nubend

Kramer

TAB

400mg

1

7.85

SUSP

200mg/5ml

10ml

12.00

Olworm

Biochem

SUSP

200mg/5ml

10ml

15.09

CHEW-TAB

400mg

1

12.07

Panamint

Seagull

TAB

400mg

5

55.00

SUSP

200mg/5ml

10ml

14.00

Tagazole

Stadmed

CHEW-TAB

400mg

1

12.00

SUSP

200mg/ml

10ml

14.50

Toko Forte

Lark

CHEW-TAB

400mg

8×3

141.04

SUSP

200mg/5ml

10ml

8.80

Ulben

Mejda

TAB

400mg

1

6.65

SUSP

200mg/5ml

10ml

8.40

WIN-400

Arvind Remedies

TAB

400mg

1

9.00

WOMIBAN

Blue Cross

TAB

400mg

1

12.00

SUSP

200mg/5ml

10ml

14.00

WORMIN-A

Cadila

TAB

400mg

1

8.00

SUSP

200mg/5ml

10ml

10.00

WORMITEL

Kamron

TAB

400mg

1

10.97

WORMPEL

Aglowmed

TAB

400mg

1

11.60

SUSP

200mg/ml

10ml

14.10

WORNIL

Mount Mettur

TAB

400mg

10ml

9.55

SUSP

400mg

12.25

XENITH

Mapra

TAB

400mg

1

9.03

TAB

400mg

4

33.00

SURUP

200mg/ml

10ml

12.30

Zelebend

German Remedies

TAB

400mg

4

40.00

Zentel

SmithKline
Beecham

TAB

400mg

1

12.25

SUSP

200mg/5ml

10ml

18.25

SUSP

200mg/5ml

50ml

53.50

Zoleban

Combat Drug

Tab

500mg

10

97.50

Top  





                                                     


                                               






 

  

Drug Information


Albedazole
  

 
Pharmacokinetics
 

Poorly absorbed from the GI tract, oral bioavailabilty being enhanced when given with a fatty meal (upto 5 fold). Its sulphoxide metabolite is widely distributed throughout the body.
 

Top

   

Indication & Dosage 

Oral : 
Hookworm Infestation Ancylostoma Duodenale necator Americanus : A single dose of 400mg. 

Children : Less than 10kg may be given 200mg as a single dose.

Roundworm (Ascaris lumbricoides) : A single dose of 400mg. 

Children : Less than 10kg may be given 200mg as a single dose. 

Threadworm (Enterobius) : A single dose of 400mg. 

Children : Less than 10kg may be given 200mg as a single dose.

Whipworm (Trichuris Trichiura) : A single dose of 400mg.

Children : Less than 10kg may be given 200mg  as a single dose.

Tapeworm (Taenia Solium T.Saginata) : 400mg/day for 3 consecutive days.

Strongyloides (s.stercoralis) : 400mg/day for 3 consecutive days.

Hydalid diseases (Echinococcus Granulosa) : 10mg/kg/day for 4-8 weeks.

Neurocysticercosis : 400mg b.i.d. for 30 days. 

Cutaneous Larva Migrans : Single dose of 400mg.

Capillaria philippinensis : 400mg b.i.d for 10-20 days. 

Infestation with opisthorchis Viverrini : 400mg b.i.d for 3 days.

Top

  

Action 

Albendazole exhibits a broad spectrum anthelmintic activity showing vermicidal, ovicidal and larvicidal action. It inhibits tubulin polymerization in the parasite and blocks glucose uptake. Energy levels are reduced  and death of the parasite results. Suscepitable parasites include hookworm , roundworm, threadworm, whipworm, tapeworm, strongyloides, opisthorchis and hydatid diseases (Echinococcus).

Top 

 

Interactions

Cimetidine / Levels of albendazole sulfoxide in bile and cystic fluid in hydatid cyst clients Dexamethasone / Possible plasma levels of albendazole sulfoxide Praziquantel / Plasma levels of albendazole sulfoxide

Top

 

Adverse Effect & Precautions
 
Nausea, vomiting, epigastric distress, abnormal LFTs, reversible alopecia.
Precaution: Hepatic and renal impairment, in neurocysticercosis patients should be receive appropriate steroid and anticonvulsant therapy.
Pregnancy: Contraindicated
Breast Feeding: Safety not established, use with caution
Man: May be used

Top 

  

 

Abex

Saga labs

TAB

400mg

1

7.20

SUSP

200mg/ml

10ml

13.00

Abz

Indoco

TAB

400mg

1

11.07

SUSP

200mg/ml

10ml

12.58

Abzole

Euphoric

TAB

400mg

2

23.50

SUSP

200mg/ml

10ml

14.00

Albazole

Wings Pharma

DISP-TAB

400mg

1

12.25

SUSP

200mg/5ml

10ml

15.00

Albendol

Micro Labs

TAB

400mg

1

9.90

SUSP

200mg/5ml

10ml

14.80

Albezole

Khandelwal

TAB

400mg

1

10.96

SUSP

200mg/5ml

10ml

16.50

Albrodo

Shalaks

TAB

400mg

1

8.00

SUSP

200mg/5ml

10ml

11.15

Alminth

Torrent

TAB

200mg

2

7.90

TAB

400mg

1

12.00

SUSP

200mg/5ml

10ml

14.90

Alzad

Merind

TAB

400mg

1

12.00

SUSP

200mg/5ml

10ml

14.07

Anthel

Lincoln

CHEW-TAB

400mg

1

9.90

SUSP

200mg/5ml

10ml

12.90

Bendex

Protec

TAB

400mg

1

11.50

SUSP

200mg/5ml

10ml

14.50

Cidazole

Juggat Pharma

TAB

400mg

1

125.25

SUSP

200mg/5ml

10ml

18.00

Combantrin

Pfizer

SUSP

200mg/5ml

10ml

14.25

Combantrin A

Pifzer

TAB

400mg

1

11.21

Elminex

Cachet Pharma

TAB

400mg

1

12.25

SUSP

200mg/5ml

10ml

15.00

Elminova

Yash

TAB

400mg

20×1

212.60

SUSP

200mg/5ml

10ml

13.61

Emanthal

M.M.Labs

TAB

400mg

1

7.50

SUSP

200mg/5ml

10ml

11.30

GEKARE

Glaxo

CAPTAB

400mg

1

8.99

SUSP

200mg/5ml

10ml

11.99

Nemofex

Pharmasynth

TAB

400mg

1

10.00

SUSP

400mg/10ml

10ml

12.75

Nemozole

IPCA

SUSP

200mg/5ml

10ml

12.00

CHEW TAB

400mg

1

9.75

Neomin

Neo Pharma

Tab

400mg

1

8.00

Nopar

Malladi Drug

Tab

400mg

1

8.00

Noworm

Alkem

TAB

400mg

1

12.00

SYRUP

400mg/10ml

10ml

14.50

Nubend

Kramer

TAB

400mg

1

7.85

SUSP

200mg/5ml

10ml

12.00

Olworm

Biochem

SUSP

200mg/5ml

10ml

15.09

CHEW-TAB

400mg

1

12.07

Panamint

Seagull

TAB

400mg

5

55.00

SUSP

200mg/5ml

10ml

14.00

Tagazole

Stadmed

CHEW-TAB

400mg

1

12.00

SUSP

200mg/ml

10ml

14.50

Toko Forte

Lark

CHEW-TAB

400mg

8×3

141.04

SUSP

200mg/5ml

10ml

8.80

Ulben

Mejda

TAB

400mg

1

6.65

SUSP

200mg/5ml

10ml

8.40

WIN-400

Arvind Remedies

TAB

400mg

1

9.00

WOMIBAN

Blue Cross

TAB

400mg

1

12.00

SUSP

200mg/5ml

10ml

14.00

WORMIN-A

Cadila

TAB

400mg

1

8.00

SUSP

200mg/5ml

10ml

10.00

WORMITEL

Kamron

TAB

400mg

1

10.97

WORMPEL

Aglowmed

TAB

400mg

1

11.60

SUSP

200mg/ml

10ml

14.10

WORNIL

Mount Mettur

TAB

400mg

10ml

9.55

SUSP

400mg

12.25

XENITH

Mapra

TAB

400mg

1

9.03

TAB

400mg

4

33.00

SURUP

200mg/ml

10ml

12.30

Zelebend

German Remedies

TAB

400mg

4

40.00

Zentel

SmithKline Beecham

TAB

400mg

1

12.25

SUSP

200mg/5ml

10ml

18.25

SUSP

200mg/5ml

50ml

53.50

Zoleban

Combat Drug

Tab

500mg

10

97.50

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By |2022-07-20T16:44:31+00:00July 20, 2022|Uncategorized|Comments Off on Albedazole

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