Drug Information

 




Artemether

  













  

Pharmacokinetics

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Indication
& dosage




IM

CHLOROQUINE-RESISTANT FALCIPARUM INFECTION; SEVERE COMPLICATED FALCIPARUM
INFECTION INCLUDING CEREBRAL MALARIA:
5-day dose scheme: Adults:
1amp(80mg) bid on day 1 followed by 1amp (80mg) OD  for the
subsequent 4 days. 

Children: 1.6mg/kg OD FOR TEH SUBSEQUENT 4
DAYS. or 3-day dose scheme: Adults: 1 amp (80mg) bid x 3 days. Children:
1.6mg/kg bid x 3 days. Children: 1.6mg/kg bid x 3 days. In either regimen,
total drug dose should not exceed 480mg for adults and 9.6mg/kg for
children.

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Action

 


It is potent & rapidly acting blood schozonticide, which is highly
efficacious in treating chloroquine-resistant falciparum malaria, &
complicated falciparum malaria including cerebral malarria. It quick onset
of effect and high efficacy in bringing down the parasite load are the
properties which make theis drug a suitable therapeutic option against
falciparum infection.

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Interaction

  

Cerebral Malaria, Chloroquine
resistant Plasmodium falciparum malariam multidrug resistant malaria

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Adverse
Effect & Precaution
 

 

Decrease in reticulocyte count,
rise of ALAT and ASAT may occur



Precaution: Not advisable to prescribe any
medicine increasing QT interval, while pt. is on artemether therapy.
Prescribed dose should not be exceeded as QT prolongation has been
reported in some cases

Pregnancy: Avoid especially in 1st trimester (May be give if
life-threatening cerebral malaria occurs).

Breast Feeding: Not Known whether excreated in milk.

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Brands
available in Market









E
Mal

Parke-Davis
INJ 150mg 30ml 3.26
Larither

IPCA
INJ 80mg 6 x 1ml 300.00
Caps 40mg 6 140.00


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Drug Information
 


Artemether
  

  
Pharmacokinetics

Top
   

Indication & dosage

IM
CHLOROQUINE-RESISTANT FALCIPARUM INFECTION; SEVERE COMPLICATED FALCIPARUM INFECTION INCLUDING CEREBRAL MALARIA:
5-day dose scheme: Adults: 1amp(80mg) bid on day 1 followed by 1amp (80mg) OD  for the subsequent 4 days. 
Children: 1.6mg/kg OD FOR TEH SUBSEQUENT 4 DAYS. or 3-day dose scheme: Adults: 1 amp (80mg) bid x 3 days. Children: 1.6mg/kg bid x 3 days. Children: 1.6mg/kg bid x 3 days. In either regimen, total drug dose should not exceed 480mg for adults and 9.6mg/kg for children.

Top
   

Action
 

It is potent & rapidly acting blood schozonticide, which is highly efficacious in treating chloroquine-resistant falciparum malaria, & complicated falciparum malaria including cerebral malarria. It quick onset of effect and high efficacy in bringing down the parasite load are the properties which make theis drug a suitable therapeutic option against falciparum infection.

Top
   

Interaction
  
Cerebral Malaria, Chloroquine resistant Plasmodium falciparum malariam multidrug resistant malaria

Top
   

Adverse Effect & Precaution 
 
Decrease in reticulocyte count, rise of ALAT and ASAT may occur

Precaution: Not advisable to prescribe any medicine increasing QT interval, while pt. is on artemether therapy. Prescribed dose should not be exceeded as QT prolongation has been reported in some cases
Pregnancy: Avoid especially in 1st trimester (May be give if life-threatening cerebral malaria occurs).
Breast Feeding: Not Known whether excreated in milk.

Top
   

E Mal

Parke-Davis

INJ

150mg

30ml

3.26

Larither

IPCA

INJ

80mg

6 x 1ml

300.00

Caps

40mg

6

140.00

Top
  

 

By |2022-07-20T16:44:51+00:00July 20, 2022|Uncategorized|Comments Off on Artemether

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