Drug Information






Artesunate

  














   

Pharmacokinetics



After administration it is
rapidly absorbed and distributed in tissues e.g liver, intestine and
kindeys. It is metabolised in liver.

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Indication
& dosage





Oral

CHLOROQUIN-RESISTANT FALCIFARUM MALARIA:
Adults: 100mg twice on day 1.
Then 50mg b.i.d. for 4 days. Children: 1.2mg/kg for 5 days. A second dose
may be given on day 1 in children with severe malaria or heavy
parasitaemia.




IM/IV

SEVERE MALARIA INCLUDING CEREBRAL MALARIA:
120mg IM OR IV on Day 1
followed by 60mg daily for 4 days. In severe cases an additional dose of
60mg may be given on Day 1,6 hrs after the first dose.

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Action

 


A potent and rapidly acting blood schizoticide derived from the leaves of
the chnese herb, Armesia annua. L. The exact mode of action is not clear
but clinical studies have confirmed the effectiveness of artesunate in P.
vivax and falciparum malaria.

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Interaction

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Adverse
Effect & Precaution 


Nausea, vomiting, itching,
dizziness, convulsions, anorexia and GI upset.



Pregnancy: Avoid except in cases of severe drug resistant malaria where
benefits clearly outweigh the potential risk.

Breast Feeding: Safety not established.

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Brands
available in Market









ARNATE

Mesco
TAB 50mg 12 180.00
FALCIGO

Cadila
Healthcare
INJ 60mg vial 162.00
TAB 60mg 4 86.52




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 Drug Information


Artesunate
  

   
Pharmacokinetics

After administration it is rapidly absorbed and distributed in tissues e.g liver, intestine and kindeys. It is metabolised in liver.

Top
 

Indication & dosage

Oral
CHLOROQUIN-RESISTANT FALCIFARUM MALARIA:
Adults: 100mg twice on day 1. Then 50mg b.i.d. for 4 days. Children: 1.2mg/kg for 5 days. A second dose may be given on day 1 in children with severe malaria or heavy parasitaemia.

IM/IV
SEVERE MALARIA INCLUDING CEREBRAL MALARIA:
120mg IM OR IV on Day 1 followed by 60mg daily for 4 days. In severe cases an additional dose of 60mg may be given on Day 1,6 hrs after the first dose.

Top
 

Action
 

A potent and rapidly acting blood schizoticide derived from the leaves of the chnese herb, Armesia annua. L. The exact mode of action is not clear but clinical studies have confirmed the effectiveness of artesunate in P. vivax and falciparum malaria.

Top
 

Adverse Effect & Precaution 
Nausea, vomiting, itching, dizziness, convulsions, anorexia and GI upset.

Pregnancy: Avoid except in cases of severe drug resistant malaria where benefits clearly outweigh the potential risk.
Breast Feeding: Safety not established.

Top
 

ARNATE

Mesco

TAB

50mg

12

180.00

FALCIGO

Cadila Healthcare

INJ

60mg

vial

162.00

TAB

60mg

4

86.52

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By |2022-07-20T16:44:50+00:00July 20, 2022|Uncategorized|Comments Off on Artesunate

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