Drug Information

 


     



Benzoyl
Peroxide


   











Pharmacokinetics



Work in vitro and in animals
(1) suggests that although there is some absorption of benzoyl peroxide
following topical application, any absorbed drug appears to be
metabolised in the skin to benzoic acid and rapidly excreted in the
urine.

 
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Indiacation
& Dosage

Topical Skin :
MILD TO MODERATE ACNE ALONE OR AS
ADJUNCT TO OTHER PREPARATIONS :
Applied over the lesions once or more
often in a day. The area should be washed and dried before application


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Action

Benzoyl peroxide is active
against propionibacterium acnes which is associated with acne.


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Interactions



PABA sun screens may
transiently discolour skin.

Tretinoin: Concomitant use may cause significant skin irritation.

   
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Adverse
Effect & Precaution




Contact allergy and local
irritation, scaling.



Precaution: Avoid contact with eyes & mucous membranes.

Pregnacy : Use with caution.

Breast Feeding: Use with caution.

Man: May be used.

   
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Brands
available in market






 










Benzac AC
GEL 2.5%  w/w    15g Galderma
GEL 5 %     w/w  15g Galderma
Pernox Gel

 
GEL 2.5 % w/w    20g CFL
GEL 5%     w/w    20g CFL
Persol Gel

 
GEL 2.5%   w/w    20g Wallace
GEL 2.5%   w/w    20g Wallace



  





   
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Drug Information
 

     
Benzoyl Peroxide
   

Pharmacokinetics

Work in vitro and in animals (1) suggests that although there is some absorption of benzoyl peroxide following topical application, any absorbed drug appears to be metabolised in the skin to benzoic acid and rapidly excreted in the urine.

    TOP 
           

Indiacation & Dosage

Topical Skin : MILD TO MODERATE ACNE ALONE OR AS ADJUNCT TO OTHER PREPARATIONS : Applied over the lesions once or more often in a day. The area should be washed and dried before application

TOP
    

Action

Benzoyl peroxide is active against propionibacterium acnes which is associated with acne.

TOP
  

Interactions

PABA sun screens may transiently discolour skin.
Tretinoin: Concomitant use may cause significant skin irritation.

    TOP 
      

Adverse Effect & Precaution

Contact allergy and local irritation, scaling.

Precaution: Avoid contact with eyes & mucous membranes.
Pregnacy : Use with caution.
Breast Feeding: Use with caution.
Man: May be used.

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Benzac AC

GEL

2.5%  w/w   

15g

Galderma

GEL

5 %     w/w 

15g

Galderma

Pernox Gel

 

GEL

2.5 % w/w   

20g

CFL

GEL

5%     w/w   

20g

CFL

Persol Gel

 

GEL

2.5%   w/w   

20g

Wallace

GEL

2.5%   w/w   

20g

Wallace

  

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By |2022-07-20T16:42:44+00:00July 20, 2022|Uncategorized|Comments Off on Benzoyl Peroxide

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