Drug Information

 


    











 

Pharmacokinetics



After administration
improvement in symptoms occurs within 60 minutes.

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Indication
& Dosage

Oral : 

I
DIOPATHIC AND POSTENCEPHALITIC PARKINSONISM ALONE OR WITH OTHER
DRUGS: 


1st week :1-1.25mg at night, 2nd week : 2-2.5mg at
night , 3rd week : 2.5mg b.i.d., 4th week : 2.5mg t.i.d then
increasing  by 2.5mg every 3-14 days are reqd. Usual  range
10-40mg daily.

Note : Normally taken with food. Elderly, same dose but with caution.

Children : Not recommended  

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Action

Bromocriptine is a dopamine
receptor agonist at D2 and D3 eceptors. Clinically bromocriptine
relieves symptoms of parkinsonism and acromegaly. It also reduces
elevated prolactin levels and restores normal gonadal functions in men
and women. Ovulatory minstrual cycles are restarted. Potassium
galactorrhoea is suppressed.

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Interactions



Antihypertensive: Efficacy
potentiated by concomitant use of bromocriptine dopamine antagonists
phenothiazines, butyrophenones: Decrease efficacy of these drugs.

Erythromcin: Increases efficacy of bromocriptine Alcohol: Decreases
tolerance to bromocriptine & vice-versa.

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Adverse
Effect &Precaution




Nausea, vomiting, postural
hypotension, skin rash, nasal congestion, headache, dyskinesia,
drowsiness and delusion.



Precaution: Hepatic, renal and cardiovascular disease. In patients with
history of Psychosis. Concomitant administration estrogen. Children,
diabetes and peptic ulcer.

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Brand
available in Market


 







 















B-crip
TAB 2.5mg 10 Chemaech
Brom
TAB 2.5mg 10 Inga
Criptal
TAB 2.5mg 10 Helios
Parlodel    
TAB 2.5mg 10 Novartis
TAB 2.5mg 4 Novartis
Proctinal     
TAB 1.25mg 10 Biddle Sawyer
TAB 2.5mg 10 Biddle Sawyer
Sicriptin    
TAB 2.5mg 1×5 Serum Institute
TAB 1.5mg 1×5 Serum Institute




  
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Drug Information
 

    

 
Pharmacokinetics

After administration improvement in symptoms occurs within 60 minutes.

TOP
 

Indication & Dosage

Oral : 
I
DIOPATHIC AND POSTENCEPHALITIC PARKINSONISM ALONE OR WITH OTHER DRUGS: 
1st week :1-1.25mg at night, 2nd week : 2-2.5mg at night , 3rd week : 2.5mg b.i.d., 4th week : 2.5mg t.i.d then increasing  by 2.5mg every 3-14 days are reqd. Usual  range 10-40mg daily.

Note : Normally taken with food. Elderly, same dose but with caution.

Children : Not recommended  

TOP
 

Action

Bromocriptine is a dopamine receptor agonist at D2 and D3 eceptors. Clinically bromocriptine relieves symptoms of parkinsonism and acromegaly. It also reduces elevated prolactin levels and restores normal gonadal functions in men and women. Ovulatory minstrual cycles are restarted. Potassium galactorrhoea is suppressed.

TOP 
 

Interactions

Antihypertensive: Efficacy potentiated by concomitant use of bromocriptine dopamine antagonists phenothiazines, butyrophenones: Decrease efficacy of these drugs.
Erythromcin: Increases efficacy of bromocriptine Alcohol: Decreases tolerance to bromocriptine & vice-versa.

TOP
 

Adverse Effect &Precaution

Nausea, vomiting, postural hypotension, skin rash, nasal congestion, headache, dyskinesia, drowsiness and delusion.

Precaution: Hepatic, renal and cardiovascular disease. In patients with history of Psychosis. Concomitant administration estrogen. Children, diabetes and peptic ulcer.

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B-crip

TAB

2.5mg

10

Chemaech

Brom

TAB

2.5mg

10

Inga

Criptal

TAB

2.5mg

10

Helios

Parlodel

 

 

TAB

2.5mg

10

Novartis

TAB

2.5mg

4

Novartis

Proctinal 

 

 

TAB

1.25mg

10

Biddle Sawyer

TAB

2.5mg

10

Biddle Sawyer

Sicriptin

 

 

TAB

2.5mg

1×5

Serum Institute

TAB

1.5mg

1×5

Serum Institute


  
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By |2022-07-20T16:44:52+00:00July 20, 2022|Uncategorized|Comments Off on Bromocriptine

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