Drug Information

 



    






   

 Pharmacokinetics

It has good
tissue penetration. Exerts more sustained action at the site of
infection .It is excreted unchanged in urine, but dose need to be
reduced only if creatinine clearance is less than 50 ml/min.




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Indication
& Dosage


 

Oral

RESPIRATORY TRACT INFFECTIONS, SKIN AND SOFT TISSUE INFECTIONS, UTI,
SINUSITIS, OTITIS MEDIA: Adult 1-2g/day as a single dose or in 2
divided doses. Children: 25-50mg/kg/day in divided doses. Children:
25-50mg/kg/day in divided doses 12 hours apart. Children under 1 year:
25mg/kg/day in divided doses 12 hours apart.

Note: Treatment is usually for 48 hours after patient becomes
asymtomatic. In infections with betahemolytic streptococci, treatment
should be continued for at least 10 days. Renal impairment: Dose
reduction based on creatinine clearance.

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Action

 


Bactericidal by inhibition of cell wall synthesis. Antibacterial
spectrum includes several Gram-positive and some Gram-negative
organisms. Susceptible Staphylococcal species include coagulase-positive
and coagulase-negative and pencillinase producing strains but not
methicillin-resistant ones. Cefadroxil is not active against Proteus,
Pseudomonas, Enterobacter, Morganella, Serratia and Listeria
monocytogenes.

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Interactions

Probenecid
increases the blood levels of many cephalosporins. Concurrent use of
furosemide increases the renal toxicity.Cefadroxil potentiates nephro
toxicity of aminoglycosides.

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Adverse
Effect & Precautions




Nause, epigastric distress,
diarrhoea, vomiting, skin rash, urticaria, genital pruritus,
pseudomembranous colitis and genital moniliasis.

Precaution to
be taken are during renal disease when the dose has to be reduced. In
Gastric and intestinal disease (especially colitis, including colitis
caused by antibiotics, or enteritis) – Cephalosporins may aggravate the
existing condition.

Pregnancy: Use with caution.

Breast Feeding: Use with caution.

Man: May be used

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BICEF

Micro Nova
DISP-TAB 500MG 10 101.22
SUSP

125mg/5ml


60ml


41.00
DISP-TAB 125mg 10 26.48
DISP-TAB 250mg 10 52.61
SUPS 125mg/ml 30ml 19.20
SUPS 250mg/ml 30ml 35.00
BID

Kopran
CAPS 500mg 4 42.15
SYRUP 250mg/ml 30ml 35.00
KID-TAB 125mg 10 26.95
KID-TAB 250mg 10 53.56
BLUDROX

Blue Cross
DISP-TAB 250mg 10 53.00
DISP-TAB 125mg

10
26.65
CAPS 500mg 10 41.70
DRY SYRUP 125mg/ml 10 18.12
CEDRO

Rekvina Pharma
TAB 125mg 10 27.14
TAB 250mg 10×10 551.00
CEDROX

Dee-Pharma
CAPS 500mg 3×10 322.80
DIS-TAB 250mg 10×10 551.00
DRY-SYRUP 125mg/5ml 30ml 19.95
CEFADROL

J.K.Ind.
DIS-TAB 250mg 4 21.60
CAPS 500mg 4 42.29
DRY-SYRUP 125mg/5ml 30ml 22.51
CEFADROX

Aristo
CAPS 500mg 6 62.86
KID-TAB 250mg 10 53.25
SYRUP 125mg/ml 30ml 19.30
KID-TAB 125mg 10 26.79
CEFADUR

Protec
CAPS 500mg 10 105.73
SUSP 250mg/5ml 30ml 35.00
DROPS 100mg/ml 10ml 35.00
DIS-TAB 125mg/5ml 6 16.87
DIS-TAB 250mg 4 17.14
CODROXIL

Comed
TAB 500mg 4 441.00
CODROXIL KID-125

Comed
KID-TAB 125mg 10×10 283.50
CODROXIL KID-250

Comed
KID-TAB 250mg 10×10 561.80
CODROXIL SUSP

Comed
SUSP 250mg/5ml 30ml 36.75
DROXIBID

Hidustan Antibiotics
TAB 500mg 4 43.46
KID-TAB 250mg 4 28.54
DROXYCEPH

Orchid
CAPS 500mg 10 85.00
DIS-TAB 125mg 10 21.25
DIS-TAB 250mg 10 42.50
DROXYL

Torrent
TAB 500mg 4 42.50







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Drug Information
 

    

   
 Pharmacokinetics

It has good tissue penetration. Exerts more sustained action at the site of infection .It is excreted unchanged in urine, but dose need to be reduced only if creatinine clearance is less than 50 ml/min.


Top
  

Indication & Dosage
 
Oral
RESPIRATORY TRACT INFFECTIONS, SKIN AND SOFT TISSUE INFECTIONS, UTI, SINUSITIS, OTITIS MEDIA: Adult 1-2g/day as a single dose or in 2 divided doses. Children: 25-50mg/kg/day in divided doses. Children: 25-50mg/kg/day in divided doses 12 hours apart. Children under 1 year: 25mg/kg/day in divided doses 12 hours apart.
Note: Treatment is usually for 48 hours after patient becomes asymtomatic. In infections with betahemolytic streptococci, treatment should be continued for at least 10 days. Renal impairment: Dose reduction based on creatinine clearance.

Top
 

Action
 

Bactericidal by inhibition of cell wall synthesis. Antibacterial spectrum includes several Gram-positive and some Gram-negative organisms. Susceptible Staphylococcal species include coagulase-positive and coagulase-negative and pencillinase producing strains but not methicillin-resistant ones. Cefadroxil is not active against Proteus, Pseudomonas, Enterobacter, Morganella, Serratia and Listeria monocytogenes.

Top
  

Interactions

Probenecid increases the blood levels of many cephalosporins. Concurrent use of furosemide increases the renal toxicity.Cefadroxil potentiates nephro toxicity of aminoglycosides.

Top
 

Adverse Effect & Precautions

Nause, epigastric distress, diarrhoea, vomiting, skin rash, urticaria, genital pruritus, pseudomembranous colitis and genital moniliasis.

Precaution to be taken are during renal disease when the dose has to be reduced. In Gastric and intestinal disease (especially colitis, including colitis caused by antibiotics, or enteritis) – Cephalosporins may aggravate the existing condition.
Pregnancy: Use with caution.
Breast Feeding: Use with caution.
Man: May be used

Top
  

BICEF

Micro Nova

DISP-TAB

500MG

10

101.22

SUSP

125mg/5ml

60ml

41.00

DISP-TAB

125mg

10

26.48

DISP-TAB

250mg

10

52.61

SUPS

125mg/ml

30ml

19.20

SUPS

250mg/ml

30ml

35.00

BID

Kopran

CAPS

500mg

4

42.15

SYRUP

250mg/ml

30ml

35.00

KID-TAB

125mg

10

26.95

KID-TAB

250mg

10

53.56

BLUDROX

Blue Cross

DISP-TAB

250mg

10

53.00

DISP-TAB

125mg

10

26.65

CAPS

500mg

10

41.70

DRY SYRUP

125mg/ml

10

18.12

CEDRO

Rekvina Pharma

TAB

125mg

10

27.14

TAB

250mg

10×10

551.00

CEDROX

Dee-Pharma

CAPS

500mg

3×10

322.80

DIS-TAB

250mg

10×10

551.00

DRY-SYRUP

125mg/5ml

30ml

19.95

CEFADROL

J.K.Ind.

DIS-TAB

250mg

4

21.60

CAPS

500mg

4

42.29

DRY-SYRUP

125mg/5ml

30ml

22.51

CEFADROX

Aristo

CAPS

500mg

6

62.86

KID-TAB

250mg

10

53.25

SYRUP

125mg/ml

30ml

19.30

KID-TAB

125mg

10

26.79

CEFADUR

Protec

CAPS

500mg

10

105.73

SUSP

250mg/5ml

30ml

35.00

DROPS

100mg/ml

10ml

35.00

DIS-TAB

125mg/5ml

6

16.87

DIS-TAB

250mg

4

17.14

CODROXIL

Comed

TAB

500mg

4

441.00

CODROXIL KID-125

Comed

KID-TAB

125mg

10×10

283.50

CODROXIL KID-250

Comed

KID-TAB

250mg

10×10

561.80

CODROXIL SUSP

Comed

SUSP

250mg/5ml

30ml

36.75

DROXIBID

Hidustan Antibiotics

TAB

500mg

4

43.46

KID-TAB

250mg

4

28.54

DROXYCEPH

Orchid

CAPS

500mg

10

85.00

DIS-TAB

125mg

10

21.25

DIS-TAB

250mg

10

42.50

DROXYL

Torrent

TAB

500mg

4

42.50

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By |2022-07-20T16:44:49+00:00July 20, 2022|Uncategorized|Comments Off on Cefadroxil

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