Drug Information

 



     






Pharmacokinetics

  


Cetirizine is rapidly absorbed from the gastrointestinal tract
after oral administration, peak plasma concentrations being
attained within about one hour. Food delays the time to peak
plasma concentrations but does not decrease the amount of drug
absorbed. It is highly bound to plasma proteins and has an
elimination half-life of about 10 hours. Cetirizine has been
detected in breast milk. Cetirizine is excreted primarily in the
urine mainly as unchanged drug. Cetirizine does not appear to
cross the blood-brain barrier to a significant extent.

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Indication
& Dosage


 


Oral

SEASONAL AND PERENNIAL ALLERGIC RHINITIS, CHRONIC IDIOPATHIC
URTICARIA, ALLERGIC CONJUNCTIVITIS, ATOPIC DERMATITIS, PRURITUS,
ADJUNT IN ASTHMA MANAGEMENT:
Adult: 10mg once or twice
daily. (2-5years): 2.5-5mg/day has been suggested. Renal
impairment: 5mg once daily.

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Action

 


A potent and highly selective antagonist of the peripheral
histamine H1-receptor. Even at high concentration there is no
effect at serotoninergic, muscarinic, dopaminergic D2 and
alphaadrenergic receptors. Has no effect at Ca2+ channels and
H2-receptors.

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Interaction

 


Alcohol: Excessive alcohol consumption.

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Adverse
Effect & Precaution

 


Headache, dizziness, dry mouth, G.I. upset, agitation.



Precaution: Renal dysfunction. Driving or operating machinery.

Pregnancy: Use with cuation.

Breast Feeding: Contraindicated.

Man: May be used in reduced dose.

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ALDAY

SOL
TAB 10MG 10 9.65
ALERID

Cipla
TAB 10mg 10 25.00
SYRUP 5mg/5ml 30ml 12.80
ALERTAC

Seagull
TAB 10mg 10 10.00
ALLERCET

Brown
& Burk
TAB 10mg 10 10.00
ALLERZINE

Jenburkt
TAB 10mg 10 12.45
ALZINE

Core
TAB 10mg 20×10 150.00
CETIN

Ind-Swift
TAB 10mg 100 275.00
CETIRIZ

Alkem
TAB 10mg 10 21.35
SYRUP 5mg/5ml 30ml 12.75
CETRINE

DR.Reddy’s
TAB 10mg 10 27.36
SYRUP 5mg/5ml 30ml 13.05
CETRIWAL

Wallace
TAB 10mg 10 15.00
CETRIZET

Sun
Pharma
TAB 5mg 10 14.00
TAB 10mg 10 24.77
CETZINE

Glaxo
Pharma
TAB 10mg 10 26.70
SYRUP 5mg/5ml 60ml 24.77
CITRAZAN

Mac
TAB 10mg 10 12.00
CLARITEC

Wander
TAB 10mg 10 10.00
COSZIN

CPL
TAB 10mg 10 24.00
SYRUP 5mg/5ml 30ml 12.50
CZ-3

Lupin
TAB 10mg 10 7.00
SYRUP 5mg/5ml 60ml 19.48
EKON
D.T.

Blue
Cross
TAB 10mg 10 21.00
EZE-DT

Saga
Labs
DISP-TAB 10mg 10 12.50
FLORAMIN

Bestochem
TABS 10mg 10 10.00
HICET

Micro
Nova
TAB 10mg 10 14.80
HISNOFIL

Crosslands
TAB 10mg 10 25.00
HISTAZIN

J.K.Ind.
TAB 10mg 10 10
HIZTIGO

Guardian
TAB 10mg 10 24.50
INCID-L

Bayer
TAB 10mg 6 14.50
JOCET

Unique
TABS 10mg 10 21.13
M-CET

Menarini
Raunaq
TAB 10mg 10 15.00
ODACET

Mapra
TAB 10mg 10 12.00
SYRUP 5mg/5ml 30ml 12.16
SYRUP 5mg/5ml 60ml 23.00
ONCET

Medley
TAB 10mg 10 16.80
RHIZIN

Recon
TAB 10mg 10 23.13
SYRUP 5mg/5ml 30ml 11.25
RINITRIN

Sigma
TAB 10mg 12×10 120.60
SATRIN

Lincoln
TAB 10mg 10 9.90
SYRUP 5mg/5ml 60ml 19.90
SIZON

Systopic
TAB 10mg 10mg .35
SYRUP 5mg/5ml 5mg/5ml 23.90
SIZON
FORTE

Systopic
TAB 20mg 10 16.65
SIZON-5

Systopic
TAB 5mg 10 6.50
SUPRES

Heilos
TAB 10mg 10 18.00
TECZINE

Croslands
TAB 10mg 10 22.50
TRIZ

Indoco
TAB 10mg 10 14.08
SYRUP 5mg/5ml 30ml 12.87
XERO-SED

Max
TAN 10mg 10 11.00
Z-CET

Centaur
TAB 10mg 10 14.09
ZETOP

Alidac
TAB 10mg 10 24.90
ZIMAT

kramer
TAB 10mg 10 11.00
ZIN-10

Advik
Lab
TAB 10mg 10 12.00
ZIN-TEN

Advik
TAB 10mg 10×10 120.00
ZIRTIN

Torrent
TAB 10mg 10 25.50
ZYNCET

Unichem
TAB 10mg 10 25.60
SUSP 5mg/5ml 60ml 24.10
ZYRTEC

UCB
Pharma
TAB 10mg 10 25.60
SYRUP 5mg/5ml 60ml 24.10





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 Drug Information
 

     

Pharmacokinetics
  

Cetirizine is rapidly absorbed from the gastrointestinal tract after oral administration, peak plasma concentrations being attained within about one hour. Food delays the time to peak plasma concentrations but does not decrease the amount of drug absorbed. It is highly bound to plasma proteins and has an elimination half-life of about 10 hours. Cetirizine has been detected in breast milk. Cetirizine is excreted primarily in the urine mainly as unchanged drug. Cetirizine does not appear to cross the blood-brain barrier to a significant extent.

TOP
  

Indication & Dosage
 

Oral
SEASONAL AND PERENNIAL ALLERGIC RHINITIS, CHRONIC IDIOPATHIC URTICARIA, ALLERGIC CONJUNCTIVITIS, ATOPIC DERMATITIS, PRURITUS, ADJUNT IN ASTHMA MANAGEMENT:
Adult: 10mg once or twice daily. (2-5years): 2.5-5mg/day has been suggested. Renal impairment: 5mg once daily.

TOP
  

Action
 

A potent and highly selective antagonist of the peripheral histamine H1-receptor. Even at high concentration there is no effect at serotoninergic, muscarinic, dopaminergic D2 and alphaadrenergic receptors. Has no effect at Ca2+ channels and H2-receptors.

TOP
  

Interaction
 

Alcohol: Excessive alcohol consumption.

TOP
  

Adverse Effect & Precaution
 

Headache, dizziness, dry mouth, G.I. upset, agitation.

Precaution: Renal dysfunction. Driving or operating machinery.
Pregnancy: Use with cuation.
Breast Feeding: Contraindicated.
Man: May be used in reduced dose.

TOP
  

ALDAY

SOL

TAB

10MG

10

9.65

ALERID

Cipla

TAB

10mg

10

25.00

SYRUP

5mg/5ml

30ml

12.80

ALERTAC

Seagull

TAB

10mg

10

10.00

ALLERCET

Brown & Burk

TAB

10mg

10

10.00

ALLERZINE

Jenburkt

TAB

10mg

10

12.45

ALZINE

Core

TAB

10mg

20×10

150.00

CETIN

Ind-Swift

TAB

10mg

100

275.00

CETIRIZ

Alkem

TAB

10mg

10

21.35

SYRUP

5mg/5ml

30ml

12.75

CETRINE

DR.Reddy’s

TAB

10mg

10

27.36

SYRUP

5mg/5ml

30ml

13.05

CETRIWAL

Wallace

TAB

10mg

10

15.00

CETRIZET

Sun Pharma

TAB

5mg

10

14.00

TAB

10mg

10

24.77

CETZINE

Glaxo Pharma

TAB

10mg

10

26.70

SYRUP

5mg/5ml

60ml

24.77

CITRAZAN

Mac

TAB

10mg

10

12.00

CLARITEC

Wander

TAB

10mg

10

10.00

COSZIN

CPL

TAB

10mg

10

24.00

SYRUP

5mg/5ml

30ml

12.50

CZ-3

Lupin

TAB

10mg

10

7.00

SYRUP

5mg/5ml

60ml

19.48

EKON D.T.

Blue Cross

TAB

10mg

10

21.00

EZE-DT

Saga Labs

DISP-TAB

10mg

10

12.50

FLORAMIN

Bestochem

TABS

10mg

10

10.00

HICET

Micro Nova

TAB

10mg

10

14.80

HISNOFIL

Crosslands

TAB

10mg

10

25.00

HISTAZIN

J.K.Ind.

TAB

10mg

10

10

HIZTIGO

Guardian

TAB

10mg

10

24.50

INCID-L

Bayer

TAB

10mg

6

14.50

JOCET

Unique

TABS

10mg

10

21.13

M-CET

Menarini Raunaq

TAB

10mg

10

15.00

ODACET

Mapra

TAB

10mg

10

12.00

SYRUP

5mg/5ml

30ml

12.16

SYRUP

5mg/5ml

60ml

23.00

ONCET

Medley

TAB

10mg

10

16.80

RHIZIN

Recon

TAB

10mg

10

23.13

SYRUP

5mg/5ml

30ml

11.25

RINITRIN

Sigma

TAB

10mg

12×10

120.60

SATRIN

Lincoln

TAB

10mg

10

9.90

SYRUP

5mg/5ml

60ml

19.90

SIZON

Systopic

TAB

10mg

10mg

.35

SYRUP

5mg/5ml

5mg/5ml

23.90

SIZON FORTE

Systopic

TAB

20mg

10

16.65

SIZON-5

Systopic

TAB

5mg

10

6.50

SUPRES

Heilos

TAB

10mg

10

18.00

TECZINE

Croslands

TAB

10mg

10

22.50

TRIZ

Indoco

TAB

10mg

10

14.08

SYRUP

5mg/5ml

30ml

12.87

XERO-SED

Max

TAN

10mg

10

11.00

Z-CET

Centaur

TAB

10mg

10

14.09

ZETOP

Alidac

TAB

10mg

10

24.90

ZIMAT

kramer

TAB

10mg

10

11.00

ZIN-10

Advik Lab

TAB

10mg

10

12.00

ZIN-TEN

Advik

TAB

10mg

10×10

120.00

ZIRTIN

Torrent

TAB

10mg

10

25.50

ZYNCET

Unichem

TAB

10mg

10

25.60

SUSP

5mg/5ml

60ml

24.10

ZYRTEC

UCB Pharma

TAB

10mg

10

25.60

SYRUP

5mg/5ml

60ml

24.10

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By |2022-07-20T16:44:48+00:00July 20, 2022|Uncategorized|Comments Off on Cetirizine

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