Drug Information

  


  


 

Diloxanide Furoate 

      













Pharmacokinetics

 




After oral administration it is rapidly absorbed and excreted rapidly in
urine.

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Indication &
Dosage

 


Oral

Cyst Eradication, Intestinal Amoebiasis: Adults: 500mg t.i.d.for 10
days. Children: 20mg/kg/day in 3 doses for 10 days.

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Action 

 


After oral intake the ester is hydrolysed in the lumen or the
mucosa of the gut. The free diloxanide acts directly as an amoebicde.
Diloxanide is given alone in asmptomatic  cyst passers. For
patients with active amoebic infections diloxanide is generally
adminstered in combination with a 5 – Nitroimidazole such as
metronidazole such as metronidazole or tinidazole.

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Interaction

 


No known Interactions.

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Adverse
Effect & Precaution




Nausea, flatulence, itching, skin rash.

 


Special precaution : Not active in hepatic amoebiasis.

Pregnancy : Contraindicated.

Brest Feeding : Use with Caution.

Men : Use with Caution.

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Brands available in
Market




 







Amicline

Franco-Indian
Tab. 500mg. 10 13.10
Furamide

Knoll Pharma
Tab. 500mg. 10 6.49



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Drug Information
  

  
  Diloxanide Furoate 
      

Pharmacokinetics
 

After oral administration it is rapidly absorbed and excreted rapidly in urine.

Top
 

Indication & Dosage
 

Oral
Cyst Eradication, Intestinal Amoebiasis: Adults: 500mg t.i.d.for 10 days. Children: 20mg/kg/day in 3 doses for 10 days.

Top

  

Action 
 

After oral intake the ester is hydrolysed in the lumen or the mucosa of the gut. The free diloxanide acts directly as an amoebicde. Diloxanide is given alone in asmptomatic  cyst passers. For patients with active amoebic infections diloxanide is generally adminstered in combination with a 5 – Nitroimidazole such as metronidazole such as metronidazole or tinidazole.

Top
  

Interaction
 

No known Interactions.

Top 
  

Adverse Effect & Precaution

Nausea, flatulence, itching, skin rash.

 
Special precaution : Not active in hepatic amoebiasis.
Pregnancy : Contraindicated.
Brest Feeding : Use with Caution.
Men : Use with Caution.

Top 
   

 

Amicline

Franco-Indian

Tab.

500mg.

10

13.10

Furamide

Knoll Pharma

Tab.

500mg.

10

6.49

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By |2022-07-20T16:42:32+00:00July 20, 2022|Uncategorized|Comments Off on Diloxanide Furoate

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