Drug Information

  

    









Pharmacokinetics

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Indication
and Dosage

Oral

MYASTHENIA
GRAVIS: 15mg on rising and before each
meal. Usual duration of action is 2-4 hrs.

ATONIC CONSTIPATION, PREVENTION AND
TREATMENT OF POST OPERATIVE DISTENTIONAND
URINARY RETENTION: 15mg q.i.d



IV

REVERSAL OF NEUROMUSCULAR BLOCK CAUSED BY
MUSCLE RELAXANTS, AMINOGLYCOSIDES AND
ANTIARRHYTHMICS: 40-50mcg/kg by slow IV
injection. Atropine 20mcg/kg to prevent
muscarinic side effects.

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Action

Inhibits
acetyl cholinesterase reversibly and
potentiates nicotinic and muscarinic
effects of acetycholine. May cause
bradycardia but BP not usually affected.

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Interactions

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Precautions

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Brands
available in market :


Name


MYOSTIGMIN

Neon
Labs

INJ 0.5mg 10x1ml 42.30
INJ 2.5mg/ml 2.5mg/ml 64.80
TILSTIGIMIN

Tablets
India

AMP 0.5mg/ml 6x1ml 27.00
TAB 15mg 10 43.20
AMP 0.5mg/ml 5x5ml 63.00

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Drug Information
  

    

Indication and Dosage

Oral
MYASTHENIA GRAVIS: 15mg on rising and before each meal. Usual duration of action is 2-4 hrs.
ATONIC CONSTIPATION, PREVENTION AND TREATMENT OF POST OPERATIVE DISTENTIONAND URINARY RETENTION: 15mg q.i.d

IV
REVERSAL OF NEUROMUSCULAR BLOCK CAUSED BY MUSCLE RELAXANTS, AMINOGLYCOSIDES AND ANTIARRHYTHMICS: 40-50mcg/kg by slow IV injection. Atropine 20mcg/kg to prevent muscarinic side effects.

Top
   

Action

Inhibits acetyl cholinesterase reversibly and potentiates nicotinic and muscarinic effects of acetycholine. May cause bradycardia but BP not usually affected.

Top
   

Brands available in market :

Name

MYOSTIGMIN

Neon Labs

INJ

0.5mg

10x1ml

42.30

INJ

2.5mg/ml

2.5mg/ml

64.80

TILSTIGIMIN

Tablets India

AMP

0.5mg/ml

6x1ml

27.00

TAB

15mg

10

43.20

AMP

0.5mg/ml

5x5ml

63.00

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