Speciality
Spotlight

 




 


Cardiology


 


   






Anticoagulant

    

  • Manon E Cromheecke, Marcel Levi, et al (Department of Cardiopulmonary Surgery, Vascular Medicine, Department of Internal Medicine, and Department of Clinical Epidemiology and Biostatistics. Academic Medical Centre, University of Amsterdam, Netherlands)

    Oral anticoagulation self-management and management by a specialist anticoagulation clinic: a randomized cross-over comparison.

    Lancet. Vol.356, July 8, 2000, p.97-102

        

    Oral anticoagulant treatment with vitamin K antagonists such as warfarin and coumarin derivatives, has been shown to be effective for the prevention and treatment of thromboembolic events. Some patients need such treatment for long periods-e.g. patients with mechanical prosthetic heart valves or patients with recurrent venous thromboembolism. Regular laboratory control and dose-adjustments are necessary.

         

    Easy and reliable laboratory devices have become available which measure prothrombin time (expressed as INR) from one drop of capillary whole blood. These devices help patients in self-testing and adjustment of dose.

      

    Fifty patients on long-term oral anticoagulant treatment were included in a randomized controlled cross-over study. They were self-managed or managed by anti-coagulation clinic for a period of 3 months. After this period they were changed over to the 2nd strategy. Prothrombin time was measured at intervals of 1-2 weeks in both periods without knowledge of type of management. End-point was the number of measurements within the therapeutic range (therapeutic target value ± 50.5 INR units).

       

    The findings showed that there was no significant difference in the overall quality of anticoagulation between the 2 study periods.

        

    Self-management of anticoagulation appears feasible and appears equivalent to management by a specialist anticoagulation centre

        




 

 

Speciality Spotlight

 

   

Anticoagulant
    

  • Manon E Cromheecke, Marcel Levi, et al (Department of Cardiopulmonary Surgery, Vascular Medicine, Department of Internal Medicine, and Department of Clinical Epidemiology and Biostatistics. Academic Medical Centre, University of Amsterdam, Netherlands)
    Oral anticoagulation self-management and management by a specialist anticoagulation clinic: a randomized cross-over comparison.
    Lancet. Vol.356, July 8, 2000, p.97-102
        
    Oral anticoagulant treatment with vitamin K antagonists such as warfarin and coumarin derivatives, has been shown to be effective for the prevention and treatment of thromboembolic events. Some patients need such treatment for long periods-e.g. patients with mechanical prosthetic heart valves or patients with recurrent venous thromboembolism. Regular laboratory control and dose-adjustments are necessary.
         
    Easy and reliable laboratory devices have become available which measure prothrombin time (expressed as INR) from one drop of capillary whole blood. These devices help patients in self-testing and adjustment of dose.
      
    Fifty patients on long-term oral anticoagulant treatment were included in a randomized controlled cross-over study. They were self-managed or managed by anti-coagulation clinic for a period of 3 months. After this period they were changed over to the 2nd strategy. Prothrombin time was measured at intervals of 1-2 weeks in both periods without knowledge of type of management. End-point was the number of measurements within the therapeutic range (therapeutic target value ± 50.5 INR units).
       
    The findings showed that there was no significant difference in the overall quality of anticoagulation between the 2 study periods.
        
    Self-management of anticoagulation appears feasible and appears equivalent to management by a specialist anticoagulation centre
        

 

By |2022-07-20T16:44:33+00:00July 20, 2022|Uncategorized|Comments Off on Anticoagulant

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