- A Angelini, V Calzolari, et al (Dept. of Pathology, Univ. of Padua Medcial School, Italy)
Myocarditis mimicking acute myocardial infarction: role of endomyocardial biopsy in the differential diagnosis.
Heart 2000; 84: 245-250.
Myocarditis can mimic acute myocardial infarction in patients with angiographically normal coronary arteries, leading to errors of treatment. In patients with apparent myocardial infarction and a normal coronary angiogram, endomyocardial biopsy may help in the diagnosis of myocarditis.
- D C G Skegg
Commentary – Hormone Therapy and Heart Disease After the Menopause
American Heart Association Recommendations on HRT and CVD
The Lancet October 13, 2001, Vol.358 (9289) Pg. 1196-1197
HRT should not be initiated for the secondary prevention of CVD.
Firm clinical recommendations for primary prevention await the results of ongoing randomised clinical trials.
There are insufficient data to suggest that HRT should be initiated for the sole purpose of primary prevention of CVD.
Initiation and continuation of HRT should be based on established noncoronary benefits and risks, possible coronary benefits.
- Jan A Staessen, Ji-Guang Wang, Lutgarde Thijs
Cardiovascular Protection and Blood Pressure Reduction: A Meta-Analysis
The Lancet October 20, 2001, Vol.358 (9290) Pg. 1305-1315
The authors’ conducted a meta-analysis of nine randomised trials comparing treatments in 62 605 hypertensive patients. Compared with old drugs (diuretics and b-blockers), calcium-channel blockers and angiotensin converting-enzyme inhibitors offered similar overall cardiovascular protection, but calcium-channel blockers provided more reduction in the risk of stroke (13.5%, 95% Cl 1.3-24.2, p=0.03) and less reduction in the risk of myocardial infarction (19.2%, 3.5-37.3, p=0.01).
The authors’ findings emphasise that blood pressure control is important. All antihypertensive drugs have similar long-term efficacy and safety.