Speciality
Spotlight

 




           

Clinical Pharmacology

       

     




  • Hugh R
    watson, Allan M Skene, & Glyn Belcher (Searle European Clinical R&D Paris, France, Nottingham Clinical Trial Data
    Centre, Nottingham & Takeda European R&D
    Centre, London, UK)


    Graft material and results of platelet inhibitor trials in peripheral arterial
    reconstrcutions: reappraisal of results from a meta-analysis.


    Br.J Clin.Pharmacol, 49, 479-483.

       


    After bypass procedures, platelet inhibitors are administered with an object of maintaining graft
    patency. The use of aspirin and related platelet inhibitors in clinical trials showed that there is little evidence that antiplatelet agents prevent occlusion of vein grafts. 

       


    It is possible that the platelet inhibitors may have some effect on the prosthetic grafts themselves.

      

  • Manon
    E Cromheecke, Marcel Levi, et al (Department of
    Cardiopulmonary Surgery, vascular
    Medicine, Department of Internal Medicine, and
    Department of Clinical Epidemiology and
    Biostatistics. Academic Medical Centre, University
    of Amsterdam, Netherlands)

    Oral
    anticoagulation self-management and management by a
    specialist anticoagulation clinic: a randomized
    cross-over comparison.

    Lancet. Vol.356, July 8, 2000, p.97-102

     

    ± 
    50.5 INR units).

     

    The
    findings showed that there was no significant
    difference in the overall quality of anticoagulation
    between the 2 study periods.

      

    Self-management
    of anticoagulation appears feasible and appears
    equivalent to management by a specialist
    anticoagulation centre.

      



  
 



 

     

Speciality Spotlight

 

           
Clinical Pharmacology
       

     

  • Hugh R watson, Allan M Skene, & Glyn Belcher (Searle European Clinical R&D Paris, France, Nottingham Clinical Trial Data Centre, Nottingham & Takeda European R&D Centre, London, UK)
    Graft material and results of platelet inhibitor trials in peripheral arterial reconstrcutions: reappraisal of results from a meta-analysis.
    Br.J Clin.Pharmacol, 49, 479-483.
       
    After bypass procedures, platelet inhibitors are administered with an object of maintaining graft patency. The use of aspirin and related platelet inhibitors in clinical trials showed that there is little evidence that antiplatelet agents prevent occlusion of vein grafts. 
       
    It is possible that the platelet inhibitors may have some effect on the prosthetic grafts themselves.
      

  • Manon E Cromheecke, Marcel Levi, et al (Department of Cardiopulmonary Surgery, vascular Medicine, Department of Internal Medicine, and Department of Clinical Epidemiology and Biostatistics. Academic Medical Centre, University of Amsterdam, Netherlands)
    Oral anticoagulation self-management and management by a specialist anticoagulation clinic: a randomized cross-over comparison.
    Lancet. Vol.356, July 8, 2000, p.97-102
     
    ±  50.5 INR units).
     
    The findings showed that there was no significant difference in the overall quality of anticoagulation between the 2 study periods.
      
    Self-management of anticoagulation appears feasible and appears equivalent to management by a specialist anticoagulation centre.
      

    

 

By |2022-07-20T16:42:13+00:00July 20, 2022|Uncategorized|Comments Off on Anticoagulance

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