Speciality
Spotlight

 




           

Clinical Pharmacology

       

     





Bladder
Tumour

    

  • M.C.Hayes, B.R. Birch, A.J. Cooper and J.N. Primrose [ Departments of Urology and University Department of Surgery, Southampton General Hospital, Southampton, UK]

    Cellular Resistance to Mitomycin C is Associated with Overexpression of MDR-1 in a Urothelial Cancer Cell Line [ MGH-U1]

    BJU International, volume 87, Number 3, February 2001, Pg.Nos. 245-250



    Conclusion – Urothelial cancer cell resistance to mitomycin C is associated with cross resistance to epirubicin and overexpression of MDR-1, suggesting that mitomycin C falls within the MDR category. Clinical application of this methodology may allow patients to be identified who are unlikely to benefit from intravesical chemotherapy






 

     

Speciality Spotlight

 

           
Clinical Pharmacology
       

     

Bladder Tumour
    

  • M.C.Hayes, B.R. Birch, A.J. Cooper and J.N. Primrose [ Departments of Urology and University Department of Surgery, Southampton General Hospital, Southampton, UK]
    Cellular Resistance to Mitomycin C is Associated with Overexpression of MDR-1 in a Urothelial Cancer Cell Line [ MGH-U1]
    BJU International, volume 87, Number 3, February 2001, Pg.Nos. 245-250

    Conclusion – Urothelial cancer cell resistance to mitomycin C is associated with cross resistance to epirubicin and overexpression of MDR-1, suggesting that mitomycin C falls within the MDR category. Clinical application of this methodology may allow patients to be identified who are unlikely to benefit from intravesical chemotherapy

 

By |2022-07-20T16:44:00+00:00July 20, 2022|Uncategorized|Comments Off on Bladder Tumour

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