Speciality
Spotlight

 




           

Clinical Pharmacology

       

     





Chronic
Stable Angina

   

  • S.
    Hashimoto, E. Yamauchi, et al (Department
    of Intensive Care, Japan
    )

    The
    pharmacokinetics of trinitroglycerin and its
    metabolites in patients with chronic stable angina.

    Br.J.Cl.
    Pharmacol. Oct.2000, 50(4), 373-376.

     

    Summary:
    Trinitroglycerin (GTN) or glyceryl trinitrate is
    widely used in patients in intensive care setting.
    It is given intravenously to patients of
    coronary artery disease. When such patients are stable and transferred to general ward, GTN
    tapes are substituted for IV GTN for convenience.

      

    This
    study has documented the pharmacokinetics of GTN and
    its metabolites during application of GTN
    transdermally and after GTN infusion in patients
    with chronic stable angina.
    The results indicate that transdermal GTN
    would maintain adequate therapeutic concentration of
    GTN after it substitutes intravenous GTN.

         



  
 



 

     

Speciality Spotlight

 

           
Clinical Pharmacology
       

     

Chronic Stable Angina
   

  • S. Hashimoto, E. Yamauchi, et al (Department of Intensive Care, Japan)
    The pharmacokinetics of trinitroglycerin and its metabolites in patients with chronic stable angina.
    Br.J.Cl. Pharmacol. Oct.2000, 50(4), 373-376.
     
    Summary: Trinitroglycerin (GTN) or glyceryl trinitrate is widely used in patients in intensive care setting. It is given intravenously to patients of coronary artery disease. When such patients are stable and transferred to general ward, GTN tapes are substituted for IV GTN for convenience.
      
    This study has documented the pharmacokinetics of GTN and its metabolites during application of GTN transdermally and after GTN infusion in patients with chronic stable angina. The results indicate that transdermal GTN would maintain adequate therapeutic concentration of GTN after it substitutes intravenous GTN.
         

    

 

By |2022-07-20T16:44:01+00:00July 20, 2022|Uncategorized|Comments Off on Chronic Stable Angina

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