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Speciality Spotlight
Drug
Evaluation
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Lowe M.N. & Lamb H.M.
Meropenem – An updated Review of its use in the Management of Intra-Abdominal Infections
Drugs, Sept 2000; 60 : 619-646
Meropenem is a carbapenem antibacterial agent with a broad spectrum of activity which encompasses Gram negative, Gram positive and anaerobic bacteria. It is resistant to beta lactamases.
In patients with moderate to severe intra-abdominal infections, empirical monotherapy with meropenem achieved clinical response rates ranging from 91% to 100% in 7 randomised comparative trials.