Speciality
Spotlight

 




           

Clinical Pharmacology

       

     





Staphylococcal
Infection

   

  • W
    Zimmerli for the Foreign-Body Infection (FBI) study group (Univ
    Hosps, Basel, Switzerland):
    Role of Rifampin for Treatment
    of Orthopedic Implant-related Staphylococcal Infections: A
    Randomized Controlled Trial
    .

    Jama
    279: 1537-1541, 1998
    .

     

    Orthopaedic
    devices are frequently infected. They
    are associated with both high morbidity and cost.
    Based on animal model, a double-blind randomised placebo
    controlled clinical trial was conducted from 1992 through 1997 to
    assess the value of rifampin containing combination antibody therapy
    for patients with a stable orthopedic implant infected with
    staphylococci.

     

    The
    clinical trial confirmed that with stable implants and short-term
    staphylococcal infections treated with initial debridement and
    long-term rifampin containing combination antibiotic therapy can be
    cured of their infection without removal of the device.

       



  
 



 

     

Speciality Spotlight

 

           
Clinical Pharmacology
       

     

Staphylococcal Infection
   

  • W Zimmerli for the Foreign-Body Infection (FBI) study group (Univ Hosps, Basel, Switzerland): Role of Rifampin for Treatment of Orthopedic Implant-related Staphylococcal Infections: A Randomized Controlled Trial.
    Jama 279: 1537-1541, 1998.
     
    Orthopaedic devices are frequently infected. They are associated with both high morbidity and cost. Based on animal model, a double-blind randomised placebo controlled clinical trial was conducted from 1992 through 1997 to assess the value of rifampin containing combination antibody therapy for patients with a stable orthopedic implant infected with staphylococci.
     
    The clinical trial confirmed that with stable implants and short-term staphylococcal infections treated with initial debridement and long-term rifampin containing combination antibiotic therapy can be cured of their infection without removal of the device.
       

    

 

By |2022-07-20T16:42:20+00:00July 20, 2022|Uncategorized|Comments Off on Staphylocaccall Infection

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