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Speciality Spotlight
Thrombosis
and Coagulation
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J-P Bossavy, et al (CHU Purpan, Toulouse, France; Sanofi Recherche, Gentilly Cedex, France; Univ of Oslo, Norway).
A Double-blind Randomized Comparison of Combined Aspirin and Ticlopidine Therapy versus Aspirin or Ticlopidine Alone on Experimental Arterial Thrombogenesis in Humans.
Blood 92: 1518-1525, 1998.
Combined aspirin and ticlopidine treatment markedly potentiates the antithrombotic effect of each drug alone. However, the antithrombotic effect of the combined treatment depends on the nature of the thrombogenic surface.