Speciality
Spotlight

 




           

Clinical Pharmacology

       

     





Viral
Diseases

   

  • M
    Rowbotham, for the Gabapentin Postherpetic Neuralgia Study Group

    Gabapentin for the Treatment of
    Postherpetic Neuralgia: A Randomized Controlled Trial.

    JAMA
    280: 1837-1842, 1998.

     


    Postherpetic neuralgia is often very difficult to treat in many
    patients.
    This article described a clinical trial in 229 patients 
    – multicentric, randomized double-blind placebo controlled.
    Patients were treated with Gabapentin and anti-epileptic
    drug. Treatment
    was given for 8 weeks and it was demonstrated that gabapentin is
    effective in postherpetic neuralgia.
    In addition the mood and quality of life improved.

     

  • E
    Kenny-Walsh, for the Irish Hepatology Research Group (Cork Univ,
    Ireland)

    Clinical
    Outcomes After Hepatitis C Infection from Contaminated Anti-D Immune
    Globulin.

    N
    Engl J Med 340: 1228-1233, 1999.

      


    After screening 62,667 women, HCV was detected in 704 women by
    PCR. Most women with HCV
    infection 17 years after receiving HCV-contaminated anti-D immune
    globulin showed inflammation on liver biopsy.
    Half had liver fibrosis, and 2% had definite cirrhosis.

      



  
 



 

     

Speciality Spotlight

 

           
Clinical Pharmacology
       

     

Viral Diseases
   

  • M Rowbotham, for the Gabapentin Postherpetic Neuralgia Study Group
    Gabapentin for the Treatment of Postherpetic Neuralgia: A Randomized Controlled Trial.
    JAMA 280: 1837-1842, 1998.
     
    Postherpetic neuralgia is often very difficult to treat in many patients. This article described a clinical trial in 229 patients  – multicentric, randomized double-blind placebo controlled. Patients were treated with Gabapentin and anti-epileptic drug. Treatment was given for 8 weeks and it was demonstrated that gabapentin is effective in postherpetic neuralgia. In addition the mood and quality of life improved.
     

  • E Kenny-Walsh, for the Irish Hepatology Research Group (Cork Univ, Ireland)
    Clinical Outcomes After Hepatitis C Infection from Contaminated Anti-D Immune Globulin.
    N Engl J Med 340: 1228-1233, 1999.
      
    After screening 62,667 women, HCV was detected in 704 women by PCR. Most women with HCV infection 17 years after receiving HCV-contaminated anti-D immune globulin showed inflammation on liver biopsy. Half had liver fibrosis, and 2% had definite cirrhosis.
      

    

 

By |2022-07-20T16:42:17+00:00July 20, 2022|Uncategorized|Comments Off on Viral Disease

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