Speciality
Spotlight

 




 


Endocrinology


   

  




Alzheimer’s
Disease

 

  


  • C
    Kawas, S Resnick, A Morrison, et al (Johns Hopkins
    Univ, Baltimore, Md; National Institute of Aging/NIH,
    Baltimore, Md; Johns Hopkins School of Hygiene and
    Public Health, Baltimore, Md)

    A
    Prospective Study of Estrogen Replacement therapy and
    the Risk of Developing Alzheimer’s Disease: 
    The Baltimore Longitudinal Study of Aging.

    Neurology
    48: 1517-1521, 1997.

       

    Estrogen
    Replacement Therapy usage appears to confer a
    protective effect regarding development of Alzheimer’s
    Disease (AD).  Estrogen
    seems to exercise a direct influence on brain
    structure and function.

       

    The
    study provides encouragement of the development of
    improved attempts to mitigate the risk of AD using new
    agents selective for tissue-specific oestrogen
    receptors.

         

  • Wolozin B, Kellman W, Ruosseau P, et al (Loyola Univ, Maywood, III; Edward Hines Jr Veterans Affairs Hosp, Hines, III; Carl T Hayden Veterans Affairs Med Ctr, Phoenix, Ariz)

    Decreased Prevalence of Alzheimer Disease Associated With 3-Hydroxy-3-Methyglutaryl Coenzyme A Reductase Inhibitors

    Arch Neurol 57: 1439-1443, 2000

         

    This study was from hospital records of 3 groups of patients who were receiving statins (lovastatin, simvastatin, or pravastatin) and patients taking medications to treat hypertension or cardiovascular diseases. Patients were aged 60 or above.

         

    It was found that lovastatin and pravastatin have a protective effect against Alzheimer’s disease. Simvastatin though chemically similar had no protective effect.

        

 



 

 

Speciality Spotlight

 

 
Endocrinology
   

  

Alzheimer’s Disease
 

  

  • C Kawas, S Resnick, A Morrison, et al (Johns Hopkins Univ, Baltimore, Md; National Institute of Aging/NIH, Baltimore, Md; Johns Hopkins School of Hygiene and Public Health, Baltimore, Md)
    A Prospective Study of Estrogen Replacement therapy and the Risk of Developing Alzheimer’s Disease:  The Baltimore Longitudinal Study of Aging.
    Neurology 48: 1517-1521, 1997.
       
    Estrogen Replacement Therapy usage appears to confer a protective effect regarding development of Alzheimer’s Disease (AD).  Estrogen seems to exercise a direct influence on brain structure and function.
       
    The study provides encouragement of the development of improved attempts to mitigate the risk of AD using new agents selective for tissue-specific oestrogen receptors.
         

  • Wolozin B, Kellman W, Ruosseau P, et al (Loyola Univ, Maywood, III; Edward Hines Jr Veterans Affairs Hosp, Hines, III; Carl T Hayden Veterans Affairs Med Ctr, Phoenix, Ariz)
    Decreased Prevalence of Alzheimer Disease Associated With 3-Hydroxy-3-Methyglutaryl Coenzyme A Reductase Inhibitors
    Arch Neurol 57: 1439-1443, 2000
         
    This study was from hospital records of 3 groups of patients who were receiving statins (lovastatin, simvastatin, or pravastatin) and patients taking medications to treat hypertension or cardiovascular diseases. Patients were aged 60 or above.
         
    It was found that lovastatin and pravastatin have a protective effect against Alzheimer’s disease. Simvastatin though chemically similar had no protective effect.
        

 

 

By |2022-07-20T16:42:14+00:00July 20, 2022|Uncategorized|Comments Off on Alzheimers Disease

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