Ferrannini Ele, (Metabolism Unit, CNR Institute of Clinical Physiology and Department of Internal Medicine, University of Pisa School of Medicine, Psia Italy).
Insulin resistance, iron, and the liver.
The Lancet Vol.355, 24 June 2000.
In Insulin-resistance syndrome (IRS), central fat accumulation (truncal or abdominal/visceral), impaired glucose metabolism (or overt diabetes mellitus), raised blood pressure (or clinical hypertension), and dyslipidaemia (typically, higher serum triglyceride concentrations along with lower serum HDL-cholesterol concentrations. Obesity as defined by the body-mass index – is not an essential component of the IRS.