Speciality
Spotlight

 




 


Endocrinology


   

  




Thyroid 
– Abortion

 

       


  • Thyroid Antibody titer and
    Avidity in Patients with Recurrent Miscarriage.


    Fertile Steril
    71:558-561, 1999
    .

       

    Several studies have reported an increased incidence
    of thyroid antibodies in the sera of women with a
    history of recurrent miscarriage.
    Thyroid antibodies may serve as a marker for
    women at risk of miscarriage. The titers of thyroid microsomal antibodies in pregnant women
    with a history of recurrent miscarriage who had
    successful pregnancies were compared with those of
    women who had unsuccessful pregnancies.

       

    Conclusions:  Autoimmunity plays a role in recurrent miscarriage. 
    Among women with a history of recurrent
    miscarriages, the humoral response to pregnancy
    appears to differ between those whose pregnancies
    continue to term and those who miscarry again.

         

    Editorial
    comments
    :
    Other studies have shown that the presence of
    antithyroid antibodies is a risk marker for
    spontaneous abortion in women with and without a
    prior history of recurrent miscarriage. All the women in this study had a history of
    recurrent miscarriage, and all had antithyroid
    antibodies. The
    data indicate that there is a direct correlation
    between the level of thyroid peroxidase antibody
    titer and avidity and subsequent miscarriage. The exact relation between elevated levels of
    thyroid peroxidase antibody and poor pregnancy
    outcome has not been determined. The presence of the antibodies may be an
    indicator of abnormal T-cell function and not a
    cause of the miscarriage.

      

 



 

 

Speciality Spotlight

 

 
Endocrinology
   

  

Thyroid  – Abortion
 

       

  • Thyroid Antibody titer and Avidity in Patients with Recurrent Miscarriage.
    Fertile Steril 71:558-561, 1999.
       
    Several studies have reported an increased incidence of thyroid antibodies in the sera of women with a history of recurrent miscarriage. Thyroid antibodies may serve as a marker for women at risk of miscarriage. The titers of thyroid microsomal antibodies in pregnant women with a history of recurrent miscarriage who had successful pregnancies were compared with those of women who had unsuccessful pregnancies.
       
    Conclusions:  Autoimmunity plays a role in recurrent miscarriage.  Among women with a history of recurrent miscarriages, the humoral response to pregnancy appears to differ between those whose pregnancies continue to term and those who miscarry again.
         
    Editorial comments: Other studies have shown that the presence of antithyroid antibodies is a risk marker for spontaneous abortion in women with and without a prior history of recurrent miscarriage. All the women in this study had a history of recurrent miscarriage, and all had antithyroid antibodies. The data indicate that there is a direct correlation between the level of thyroid peroxidase antibody titer and avidity and subsequent miscarriage. The exact relation between elevated levels of thyroid peroxidase antibody and poor pregnancy outcome has not been determined. The presence of the antibodies may be an indicator of abnormal T-cell function and not a cause of the miscarriage.
      

 

 

By |2022-07-20T16:43:37+00:00July 20, 2022|Uncategorized|Comments Off on Thyroid Abortion

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