Thyroid Abortion

Thyroid 
– Abortion

 

• Thyroid Antibody titer and
  Avidity in Patients with Recurrent Miscarriage.
  
  Fertile Steril
  71:558-561, 1999.
  
     
  
  Several studies have reported an increased incidence
  of thyroid antibodies in the sera of women with a
  history of recurrent miscarriage.
  Thyroid antibodies may serve as a marker for
  women at risk of miscarriage. The titers of thyroid microsomal antibodies in pregnant women
  with a history of recurrent miscarriage who had
  successful pregnancies were compared with those of
  women who had unsuccessful pregnancies.
  
     
  
  Conclusions:  Autoimmunity plays a role in recurrent miscarriage. 
  Among women with a history of recurrent
  miscarriages, the humoral response to pregnancy
  appears to differ between those whose pregnancies
  continue to term and those who miscarry again.
  
       
  
  Editorial
  comments:
  Other studies have shown that the presence of
  antithyroid antibodies is a risk marker for
  spontaneous abortion in women with and without a
  prior history of recurrent miscarriage. All the women in this study had a history of
  recurrent miscarriage, and all had antithyroid
  antibodies. The
  data indicate that there is a direct correlation
  between the level of thyroid peroxidase antibody
  titer and avidity and subsequent miscarriage. The exact relation between elevated levels of
  thyroid peroxidase antibody and poor pregnancy
  outcome has not been determined. The presence of the antibodies may be an
  indicator of abnormal T-cell function and not a
  cause of the miscarriage.