Speciality
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Family Practice


 

 




Vascular Disease 

 

  • Carotid Artery Disease

    Mackey AE, and the Asymptomatic Cervical Bruit Study Group [Laval Univ, Quebec; McGill Univ, Montreal Gen Hosp]


    Outcome of Asymptomatic Patients With Carotid Disease


    Neurology 48:896-903, 1997

       


    715 patients with asymptomatic cervical bruits at an average of 65 years were followed up for about 3.6 years. Subjects had arterial narrowing due to atherosclerosis. With stenosis less than 50% the incidence of neurologic episodes was 4.2 and beyond 50% was 11%. Annual stroke and vascular death were 1.9% and 5.5% respectively. A marked increase was observed with stenosis over 80%. Control of hypertension and smoking are suggested to prevent progression of disease.

         
  • Decousus H, for the Prevention du Risque d’Embolie Pulmonaire par interuption Cave Study Group [Bellevue Hosp, Saint-Etiemme, France; Cardiological Hosp, Lyons, France; Antoine Beclere Hosp, Clamart, France; et al]


    A Clinical Trial of Vena Caval Filters in the Prevention of Pulmonary Embolism in Patients With Proximal Deep-Vein Thrombosis


    N Engl J Med 338: 409-415, 1998

       


    400 patients with proximal deep-vein thrombosis and thus at risk of pulmonary embolism were studied. All of them received low molecular weight heparin or unfractionated heparin. One group received the filter and the other did not. On the 12th day those with filters had a pulmonary embolism rate of 1.1% and the other 4.8%. By 2 years the rates were 20.8% and 11.6% respectively. Mortality and other outcomes were the same in the two groups. Low-molecular weight heparin and unfractionated heparin were effective in prevention of embolism.

       


    A short lerim benefit of filter is counterbalanced by a greater incidence of recurrence of proximal deep vein thrombosis in the long run.

        
  • Wolfe TR, Allen TL [Univ of Utah, Salt Lake City; Univ of Pittsburgh, Pal


    Syncope as an Emergency Department Presentation of Pulmonary Embolism 


    J Emerg Med 16:27-31, 1998

       


    A 38 year man suffering from hypertension receiving diltiazem, atenolol and chlorthalidone without any risk factors for pulmonary embolism is described as developing dizziness as the sole symptom. He died and the diagnosis was made at autopsy.

       




 

 

Speciality Spotlight

 

 

Vascular Disease 
 

  • Carotid Artery Disease
    Mackey AE, and the Asymptomatic Cervical Bruit Study Group [Laval Univ, Quebec; McGill Univ, Montreal Gen Hosp]
    Outcome of Asymptomatic Patients With Carotid Disease
    Neurology 48:896-903, 1997
       
    715 patients with asymptomatic cervical bruits at an average of 65 years were followed up for about 3.6 years. Subjects had arterial narrowing due to atherosclerosis. With stenosis less than 50% the incidence of neurologic episodes was 4.2 and beyond 50% was 11%. Annual stroke and vascular death were 1.9% and 5.5% respectively. A marked increase was observed with stenosis over 80%. Control of hypertension and smoking are suggested to prevent progression of disease.
         
  • Decousus H, for the Prevention du Risque d’Embolie Pulmonaire par interuption Cave Study Group [Bellevue Hosp, Saint-Etiemme, France; Cardiological Hosp, Lyons, France; Antoine Beclere Hosp, Clamart, France; et al]
    A Clinical Trial of Vena Caval Filters in the Prevention of Pulmonary Embolism in Patients With Proximal Deep-Vein Thrombosis
    N Engl J Med 338: 409-415, 1998
       
    400 patients with proximal deep-vein thrombosis and thus at risk of pulmonary embolism were studied. All of them received low molecular weight heparin or unfractionated heparin. One group received the filter and the other did not. On the 12th day those with filters had a pulmonary embolism rate of 1.1% and the other 4.8%. By 2 years the rates were 20.8% and 11.6% respectively. Mortality and other outcomes were the same in the two groups. Low-molecular weight heparin and unfractionated heparin were effective in prevention of embolism.
       
    A short lerim benefit of filter is counterbalanced by a greater incidence of recurrence of proximal deep vein thrombosis in the long run.
        
  • Wolfe TR, Allen TL [Univ of Utah, Salt Lake City; Univ of Pittsburgh, Pal
    Syncope as an Emergency Department Presentation of Pulmonary Embolism 
    J Emerg Med 16:27-31, 1998
       
    A 38 year man suffering from hypertension receiving diltiazem, atenolol and chlorthalidone without any risk factors for pulmonary embolism is described as developing dizziness as the sole symptom. He died and the diagnosis was made at autopsy.
       

 

By |2022-07-20T16:43:29+00:00July 20, 2022|Uncategorized|Comments Off on Vascular Disease

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