RF Kroidi, D Gobel, D Balzer, et al (Stade, Germany)
Clinical Effects of Benzyl Benzoate in the Prevention of House-Dust-Mite Allergy: Results of a Prospective, Double-blind, Multicenter Study.
Allergy 53: 435-440, 1998.
The efficacy of the acaricide benzyl benzoate is controversial. Earlier studies bolstered by laboratory findings have showed positive results whereas other studies have shown no benefit over the achieved by the vehicle alone. This particular study reported shows no benefit in objective measures in 118 asthmatic patients sensitive to D.pteronyssinus. Subjective improvements were found in about 50% of both the active and placebo groups. However the only issue of question or questionable or debatable point is that the authors state that the patients were instructed to follow package instructions for the use of this particular acaricide. However, it was not followed, whether these patients actually did follow the orders as instructed, in which case this may have been less effective utilisation of the agent.