Anesthesia In Cirrhosis

Anesthesia
in Cirrhosis of Liver-Increased
Morbidity and Mortality

  

• Ziser
  A, Plevak DJ, Wiesner RH, et al
  
  Morbidity and Mortality in Cirrhotic Patients
  undergoing Anesthesia and Surgery
  
  Anesthesiology
  90: 42-53, 1999
  
   
  
  Patients
  with cirrhosis of liver who undergo anesthesia and
  surgery have an increased mortality rate.
  Factors that might predict perioperative
  complications and death in such patients were
  retrospectively investigated.
  
   
  
  Results
  showed, postoperative complications, most commonly
  pneumonia, occurred in 222 patients [30.1%].
  There were 72 in – hospital deaths [9.8%],
  and 13 out-of-hospital deaths [1.8%], within 30 days
  of surgery. Most
  of the deaths occurred in the immediate
  post-operative period; 8 variables were associated
  with death and included male sex, a high Child-Pugh
  score, ascites, cryptogenic cirrhosis, elevated
  creatinine level, preoperative infection, a high ASA
  status, and respiratory surgery.