in Cirrhosis of Liver-Increased
Morbidity and Mortality
Ziser A, Plevak DJ, Wiesner RH, et al
Morbidity and Mortality in Cirrhotic Patients undergoing Anesthesia and Surgery
Anesthesiology 90: 42-53, 1999
Patients with cirrhosis of liver who undergo anesthesia and surgery have an increased mortality rate. Factors that might predict perioperative complications and death in such patients were retrospectively investigated.
Results showed, postoperative complications, most commonly pneumonia, occurred in 222 patients [30.1%]. There were 72 in – hospital deaths [9.8%], and 13 out-of-hospital deaths [1.8%], within 30 days of surgery. Most of the deaths occurred in the immediate post-operative period; 8 variables were associated with death and included male sex, a high Child-Pugh score, ascites, cryptogenic cirrhosis, elevated creatinine level, preoperative infection, a high ASA status, and respiratory surgery.