Speciality
Spotlight

       




 


Medicine


   

 




Anticoagulant

   

  • Manon
    E Cromheecke, Marcel Levi, et al (Department of
    Cardiopulmonary Surgery, vascular
    Medicine, Department of Internal Medicine, and
    Department of Clinical Epidemiology and
    Biostatistics. Academic Medical Centre, University
    of Amsterdam, Netherlands)

    Oral
    anticoagulation self-management and management by a
    specialist anticoagulation clinic: a randomized
    cross-over comparison.

    Lancet.
    Vol.356, July 8, 2000, p.97-102

      

    Oral
    anticoagulant treatment with vitamin K antagonists
    such as warfarin and coumarin derivatives, has been
    shown to be effective for the prevention and
    treatment of
    thromboembolic events.
    Some patients need such treatment for long
    periods-e.g. patients with mechanical prosthetic
    heart valves or patients with recurrent venous
    thromboembolism. Regular
    laboratory control and dose-adjustments are
    necessary.

      

    Easy
    and reliable laboratory devices have become
    available which measure prothrombin time (expressed
    as INR) from one drop of capillary whole blood. these
    devices help patients in self-testing and adjustment
    of dose.

       

    Fifty
    patients on long-term oral anticoagulant treatment
    were included in a randomized controlled cross-over
    study. They
    were self-managed or managed by anti-coagulation
    clinic for a period of 3 months.
    After this period they were changed over to
    the 2nd strategy. Prothrombin
    time was measured at intervals of 1-2 weeks in both
    periods without knowledge of type of management.
    End-point was the number of measurements
    within the therapeutic range (therapeutic target
    value
    ± 
    50.5 INR units).

       

    The
    findings showed that there was no significant
    difference in the overall quality of anticoagulation
    between the 2 study periods.

      

    Self-management
    of anticoagulation appears feasible and appears
    equivalent to management by a specialist
    anticoagulation centre.

             

 



 

           

Speciality Spotlight

       

 
Medicine
   

 

Anticoagulant
   

  • Manon E Cromheecke, Marcel Levi, et al (Department of Cardiopulmonary Surgery, vascular Medicine, Department of Internal Medicine, and Department of Clinical Epidemiology and Biostatistics. Academic Medical Centre, University of Amsterdam, Netherlands)
    Oral anticoagulation self-management and management by a specialist anticoagulation clinic: a randomized cross-over comparison.
    Lancet. Vol.356, July 8, 2000, p.97-102
      
    Oral anticoagulant treatment with vitamin K antagonists such as warfarin and coumarin derivatives, has been shown to be effective for the prevention and treatment of thromboembolic events. Some patients need such treatment for long periods-e.g. patients with mechanical prosthetic heart valves or patients with recurrent venous thromboembolism. Regular laboratory control and dose-adjustments are necessary.
      
    Easy and reliable laboratory devices have become available which measure prothrombin time (expressed as INR) from one drop of capillary whole blood. these devices help patients in self-testing and adjustment of dose.
       
    Fifty patients on long-term oral anticoagulant treatment were included in a randomized controlled cross-over study. They were self-managed or managed by anti-coagulation clinic for a period of 3 months. After this period they were changed over to the 2nd strategy. Prothrombin time was measured at intervals of 1-2 weeks in both periods without knowledge of type of management. End-point was the number of measurements within the therapeutic range (therapeutic target value
    ±  50.5 INR units).
       
    The findings showed that there was no significant difference in the overall quality of anticoagulation between the 2 study periods.
      
    Self-management of anticoagulation appears feasible and appears equivalent to management by a specialist anticoagulation centre.
             

 

 

By |2022-07-20T16:41:26+00:00July 20, 2022|Uncategorized|Comments Off on Anticoagulant

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