Speciality
Spotlight

       




 


Medicine


   

 




C-Reactive Proteins
and Adverse Operative Outcomes

  


  • Goranson J, Jonsson S, Lasson A


    Screening of Concentrations of C-Reactive Protein and Various Plasma Protease Inhibitors Preoperatively for the Prediction of Postoperative Complications


    Eur J Surg 164: 89-101, 1998

     


    A number of methods have been used to try to predict which patients are at risk of postoperative complications and death, but so far no cheap and sensitive test has been developed. The prognostic value of low blood albumin, a high C-reactive protein [CRP] level or deficient plasma protease inhibitors and the ability of other biochemical tests to prognosticate postoperative outcomes, were evaluated retrospectively in a Swedish hospital. 

     


    Before elective surgery, biochemical plasma measurements were performed in 260 patients, 149 with malignant disease. Postoperative complications and length of hospital stay were noted. 

     


    There was a significant difference between all patient groups with regard to median hospital stay, which was 26 days for patients with major complications. 9 days for those with minor complications and 7 days for those with no complications. Preoperative Albumin concentrations were significantly lower in patients with major complications than the rest. Preoperative CRP concentrations were significantly higher in patients with major complications than the rest. Other factors such as C1-esterase inhibitor, alpha-2-macroglobulin, or antithrombin III values, agarose gel electrophoresis and protease-antiprotease complexes had no significant differences in the various groups. 

     

    Preoperative CRP and Albumin levels accurately identify patients at risk of postoperative complications.

        

 



 

           

Speciality Spotlight

       

 
Medicine
   

 

C-Reactive Proteins and Adverse Operative Outcomes
  

  • Goranson J, Jonsson S, Lasson A
    Screening of Concentrations of C-Reactive Protein and Various Plasma Protease Inhibitors Preoperatively for the Prediction of Postoperative Complications
    Eur J Surg 164: 89-101, 1998
     
    A number of methods have been used to try to predict which patients are at risk of postoperative complications and death, but so far no cheap and sensitive test has been developed. The prognostic value of low blood albumin, a high C-reactive protein [CRP] level or deficient plasma protease inhibitors and the ability of other biochemical tests to prognosticate postoperative outcomes, were evaluated retrospectively in a Swedish hospital. 
     

    Before elective surgery, biochemical plasma measurements were performed in 260 patients, 149 with malignant disease. Postoperative complications and length of hospital stay were noted. 
     
    There was a significant difference between all patient groups with regard to median hospital stay, which was 26 days for patients with major complications. 9 days for those with minor complications and 7 days for those with no complications. Preoperative Albumin concentrations were significantly lower in patients with major complications than the rest. Preoperative CRP concentrations were significantly higher in patients with major complications than the rest. Other factors such as C1-esterase inhibitor, alpha-2-macroglobulin, or antithrombin III values, agarose gel electrophoresis and protease-antiprotease complexes had no significant differences in the various groups. 
     
    Preoperative CRP and Albumin levels accurately identify patients at risk of postoperative complications.
        

 

 

By |2022-07-20T16:42:08+00:00July 20, 2022|Uncategorized|Comments Off on C – Reactive Proteins

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