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Speciality Spotlight
Dialysis
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AF De Vecchi, M Maccario, M Braga, et al (IRCCS Ospedale Maggiore, Milan, Italy) Peritoneal Dialysis in Nondiabetic Patients Older Than 70 years: Comparison with Patients Aged 40 to 60 years.
Am J Kidney Dis 31:479-490, 1998
In this study comparing elderly and younger patients with end-stage renal disease undergoing continuous ambulatory peritoneal dialysis at the same center, there was no significant difference in complications, peritoneal function, or age-specific survival rate. These results indicate elderly patients are good candidates for Ambulatory Peritoneal Dialysis and should not be excluded on the basis of age alone.
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A Aguilera, R Codoceco, R Selgas, et al (Hosp. Universitario La Paz, Madrid). Anorexigen (TNF-a, Cholecystokinin) and Orexigen (Neuropeptide Y) Plasma Levels in Peritoneal Dialysis (PD) Patients: Their Relationship with Nutritional Parameters.
Nephrol Dial Transplant 13:1476-1483, 1998.
Several studies of dialysis patients have documented a high prevalence of protein-energy malnutrition in patients undergoing hemodialysis or PD. The tendency toward a negative nitrogen balance and muscle wasting in this population is related to several factors including anorexia and increased degradation of protein and amino acids as a consequence of uremia.
Anorexia is perhaps one of the most important causes of malnutrition in uremic patients. Several factors have been implicated in its pathogenesis. These include insufficient dialysis, infection, certain drugs, gastropathy, and socioeconomic factors.
