|
Speciality Spotlight
Immunity
-
F Altare, A Durandy, D Lammas et al (Hopital Necker-Enfants Malades, Paris; Univ of Birmingham, England; Hopital Paul Brousse, Villejuif, France, et al) :
Impairment of Mycobacterial Immunity In Human Interleukin-12 Receptor Deficiency.
Science 280:1432-1435, 1998.
Interferon-gamma (IFN-g) receptor deficiency results in predisposition to mycobacterial infections. It also impairs the formation of mature granulomas. The formation of mature granulomas is one of the important factors for development of mycobacterial immunity.