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Speciality Spotlight
Alzheimer’s Disease
- Wolozin B, Kellman W, Ruosseau P, et al (Loyola Univ, Maywood, III; Edward Hines Jr Veterans Affairs Hosp, Hines, III; Carl T Hayden Veterans Affairs Med Ctr, Phoenix, Ariz)
Decreased Prevalence of Alzheimer Disease Associated With 3-Hydroxy-3-Methyglutaryl Coenzyme A Reductase Inhibitors
Arch Neurol 57: 1439-1443, 2000
This study was from hospital records of 3 groups of patients who were receiving statins (lovastatin, simvastatin, or pravastatin) and patients taking medications to treat hypertension or cardiovascular diseases. Patients were aged 60 or above.
It was found that lovastatin and pravastatin have a protective effect against Alzheimer’s disease. Simvastatin though chemically similar had no protective effect.