Speciality
Spotlight

 




 


Oncology


 

 





Liver
Failure

     

  • Ronnie
    Tung-Ping Poon, Sheung-Tat Fan, et al (The Centre of
    Liver Diseases, Department of Surgery and Pathology, The
    University of Hong Kong Medical Centre, Queen Mary
    Hospital, Hong Kong, China).

    Significance
    of Resection Margin in Hepatectomy for Hepatocellular
    Carcinoma.

    A Critical Reappraisal

    Annals of Surgery, April 2000, 231(4), 544-551.

       


    This study evaluates the influence of the width and
    the histologic involvement of the resection margin on
    postoperative recurrence after resection of
    hepatocellular carcinoma (HCC).

       

    288
    patients with macroscopically complete resection of HCC
    were divided into 2 groups with narrow (< 1cm) or
    wide (
    ³
    1cm) resection margins, and compared.

       

    The
    recurrence rates were similar between the two groups and
    they were similar in other clinicopathologic variables.

       

    Most
    recurrences occurred away from the resection margin or
    at multiple sites. Those
    who had histologically involved resection margin or
    venous tumour emboli or multisatellites had higher
    recurrence rates then those without.

       

    However,
    a positive histologic margin was not a significant risk
    factor for recurrence by multivariate analysis.
    The tumour stage and the perioperative
    transfusion were the only independent risk factor.

        

    They
    conclude that the width of the resection margin did not
    influence the post-operative recurrence rate after
    hepatectomy for HCC. Most
    recurrences were considered to arise from venous
    dissemination.

        


 

 



 

 

Speciality Spotlight

 

 

Liver Failure
     

  • Ronnie Tung-Ping Poon, Sheung-Tat Fan, et al (The Centre of Liver Diseases, Department of Surgery and Pathology, The University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, China).
    Significance of Resection Margin in Hepatectomy for Hepatocellular Carcinoma.
    A Critical Reappraisal
    Annals of Surgery, April 2000, 231(4), 544-551.
       
    This study evaluates the influence of the width and the histologic involvement of the resection margin on postoperative recurrence after resection of hepatocellular carcinoma (HCC).
       
    288 patients with macroscopically complete resection of HCC were divided into 2 groups with narrow (< 1cm) or wide (
    ³ 1cm) resection margins, and compared.
       
    The recurrence rates were similar between the two groups and they were similar in other clinicopathologic variables.
       
    Most recurrences occurred away from the resection margin or at multiple sites. Those who had histologically involved resection margin or venous tumour emboli or multisatellites had higher recurrence rates then those without.
       
    However, a positive histologic margin was not a significant risk factor for recurrence by multivariate analysis. The tumour stage and the perioperative transfusion were the only independent risk factor.
        
    They conclude that the width of the resection margin did not influence the post-operative recurrence rate after hepatectomy for HCC. Most recurrences were considered to arise from venous dissemination.
        

 

 

 

By |2022-07-20T16:42:21+00:00July 20, 2022|Uncategorized|Comments Off on Liver Failure

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