& Herpes Simplex Virus Keratitis
- Holland EJ, Schwartz GS (Univ of Minnesota, Minneapolis)
Classification of Herpes Simplex Virus Keratitis.
Cornea 18: 144-154, 1999
The authors propose a different classification system based on the anatomy and pathophysiology of the specific presentations of herpes simplex virus (HSV) keratitis.
The anatomical parameters are according to the level of corneal involvement viz, epithelial, stromal and endothelial.
The pathophysiological classification is according to the cause of inflammation viz immunologic infections or neurotrophic.
There are 4 major categories of HSV keratitis:
(1) Infectious epithelial keratitis – consisting of (a) corneal vesicles (b) dendritic ulcer (c) geographic ulcer (d) marginal ulcer.
(2) Neurotrophic keratopathy – which includes punctuate epithelial erosions and neurotrophic ulceration.
(3) Stromal keratitis which may be (a) necrotizing stromal keratitis or (b) immune stromal keratitis.
(4) Endotheliitis presenting as disciform, diffuse or linear form.