Glaucoma, Pseudoexfoliation

Glaucoma,
Pseudoexfoliation

     

• GOH
  Naumann, U Schlotzer-Scherhardt, M Kuchle (Univ of
  Erlangen-Nurnberg, Germany)
  
  Pseudoexfoliation Syndrome for
  the Comprehensive Ophthalmologist:
  
  Ophthalmology
  105:951-968, 1998.
  
    
  
  Pseudoexfoliation syndrome is both an
  ocular and a generalized disorder involving abnormal
  production and/or turnover of extracellular matrix
  material. All
  tissues of the anterior segment of the eye and
  extraocular tissues are involved.
  This syndrome should be suspected when the
  patient has circular or segmental posterior
  synechiae without any other obvious cause.
  
    
  
  Slit-lamp
  examination, biocytology and laser-tyndallometry are
  used for clinical diagnosis.
  
     
  
  The
  zonular apparatus, lens, iris, ciliary body, cornea
  and the trabecular meshwork are involved in this
  clinical entity. 
  Complications reviewed include phacodonesis,
  lens dislocation, increased incidence of vitreous
  loss in extracapsular cataract extraction caused by
  alterations in the zonules.
  Open angle as well as angle-closure glaucoma
  may occur. Early
  diffuse corneal endothelial decompensation, anterior
  chamber hypoxia, iris stroma haemorrhage, poor or
  asymmetric mydriasis and posterior synechiae are the
  various clinical manifestations.