H.K. Wu et al (Tufts Univ. School of Medicine, New England Eye Centre, Boston, MA)
Late occurrence of Diffuse Lamellar Keratitis After Laser in Situ Keratomileusis.
Arch.Ophthalmology, vol.119, July 2001: 1074-1076
Diffuse Lamellar Keratitis (DLK) is a non-infectious inflammatory complication associated with LASIK, also described as “Sands of Sahara Syndrome” and central focal interface opacity.
This condition is commonly reported to occur within 1 month after LASIK treatment, enhancement or flap manipulation, or epithelial flap debridement (to reduce basement membrane irregularities).
The authors report 2 cases of DLK appearing 2 to 7 months after LASIK.
The estimated incidence of DLK is 3 in 400 cases. Four clinical stages have been described, ranging from non-visually significant focal infiltrates to diffuse infiltrates with stromal necrosis.
DLK has a good prognosis for recovery, following intensive topical steroid therapy.