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Otolaryngology


 

    

  




Cochlea

  

  • NA
    Shirwany, MD Seidman, W Tang, (Henry Ford Health System, Detroit)


    Effect of Transtympanic Injection of Steroids on Cochlear Blood Flow, Auditory Sensitivity, and Histology in the Guinea Pig.



    Am J Otol 19:230-235, 1998. 


       


    Steroids are usually administered parenterally or orally. There is evidence of significantly higher levels of steroid in the perilymph, after transtympanic injection. In the latter mode of administration, systemic side effects of steroids are avoided.

       


    The effect of transtympanic injection of dexamethasone on cochlear blood flow, auditory sensitivity, and histologic effects in the guinea-pig were examined. The findings indicate that transtympanic administration of steroids does NOT damage the inner ear. The increase in cochlear blood flow was sustained for at least one hour after application of the drug.

         

 



 

Speciality Spotlight

 

    
  

Cochlea
  

  • NA Shirwany, MD Seidman, W Tang, (Henry Ford Health System, Detroit)
    Effect of Transtympanic Injection of Steroids on Cochlear Blood Flow, Auditory Sensitivity, and Histology in the Guinea Pig.
    Am J Otol 19:230-235, 1998. 
       
    Steroids are usually administered parenterally or orally. There is evidence of significantly higher levels of steroid in the perilymph, after transtympanic injection. In the latter mode of administration, systemic side effects of steroids are avoided.
       
    The effect of transtympanic injection of dexamethasone on cochlear blood flow, auditory sensitivity, and histologic effects in the guinea-pig were examined. The findings indicate that transtympanic administration of steroids does NOT damage the inner ear. The increase in cochlear blood flow was sustained for at least one hour after application of the drug.
         

 

 

By |2022-07-20T16:43:18+00:00July 20, 2022|Uncategorized|Comments Off on Cochlea

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