- Perricone NV (Meriden, Conn)
Topical 5% Alpha Lipoic Acid Cream in the Treatment of Cutaneous Rhytids
Aesthetic Surg J 20: 218-222, 2000
a Lipoic acid is a potent antioxidant agent that rapidly penetrates the skin. The effects of this cream on actinic-damaged and aged skin were evaluated.
15 patients were treated. The patients were asked to apply cream twice a day for 12 weeks.
It effected striking reduction in facial lines. These improvements were effective without any irritation or adverse side effect.